Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14031260 | 0.84 | EPHX1 (0.52) | EPHX1POLB | |
| SCHEMBL21727769 | 0.78 | EPHX1 (0.38) | EPHX1POLB | |
| SCHEMBL24261268 | 0.77 | EPHX1 (0.39) | EPHX1POLBPIK3CD | |
| SCHEMBL20384036 | 0.77 | EPHX1 (0.39) | EPHX1POLB | |
| SCHEMBL14753270 | 0.77 | EPHX1 (0.35) | EPHX1POLB | |
| SCHEMBL1526199 | 0.76 | POLB (0.43) | EPHX1POLB | |
| SCHEMBL17975428 | 0.76 | EPHX1 (0.52) | EPHX1POLB | |
| SCHEMBL20384022 | 0.75 | EPHX1 (0.34) | EPHX1 | |
| SCHEMBL23760256 | 0.75 | EPHX1 (0.36) | EPHX1 | |
| SCHEMBL24067434 | 0.74 | EPHX1 (0.33) | EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2426108-A1 | Processes and intermediates for preparing fused heterocyclic kinase inhibitors | MethylGene Inc. (CA) | 2012-03-07 | — | — | EP | disclosed |