Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPA1 | P27694 | 1/20 | 0.54 |
| ▸ | CNR1 | P21554 | 6/20 | 0.50 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MARS1 | P56192 | 6/20 | 0.48 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17203554 | 0.95 | OPRL1 (0.54) | RPA1CNR1OPRL1CNR2MEN1 | |
| SCHEMBL17204181 | 0.91 | MEN1 (0.51) | RPA1CNR1OPRL1CNR2MEN1 | |
| SCHEMBL17203516 | 0.91 | CNR1 (0.47) | RPA1CNR1OPRL1CNR2MEN1 | |
| SCHEMBL17206139 | 0.89 | MEN1 (0.47) | RPA1CNR1OPRL1CNR2MEN1 | |
| SCHEMBL17203501 | 0.89 | MEN1 (0.47) | RPA1CNR1OPRL1CNR2MEN1 | |
| SCHEMBL17203723 | 0.87 | CNR1 (0.53) | CNR1OPRL1CNR2MARS1FAAH | |
| SCHEMBL17203717 | 0.86 | RPA1 (0.56) | RPA1CNR1OPRL1CNR2MEN1 | |
| SCHEMBL17203647 | 0.85 | RPA1 (0.58) | RPA1CNR1OPRL1CNR2MEN1 | |
| SCHEMBL17203709 | 0.83 | RPA1 (0.55) | RPA1CNR1OPRL1CNR2MEN1 | |
| SCHEMBL17203334 | 0.83 | MEN1 (0.41) | RPA1CNR1CNR2MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015162452-A1 | SUBSTITUTED PYRAZOLE COMPOUNDS AS CB1 RECEPTOR ANTAGONISTS AND USES THEREOF | Piramal Enterprises Limited (IN) | 2015-10-29 | — | — | WO | claimed |
| WO-2015162452-A1 | SUBSTITUTED PYRAZOLE COMPOUNDS AS CB1 RECEPTOR ANTAGONISTS AND USES THEREOF | Piramal Enterprises Limited (IN) | 2015-10-29 | — | — | WO | disclosed |