Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KB | Q9UBF8 | 5/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL655035 | 0.95 | CNR1 (0.51) | PI4KBCNR1ALDH1A1MAPTNPSR1 | |
| SCHEMBL653219 | 0.92 | PI4KB (0.53) | PI4KBALDH1A1MAPTNPSR1MAPK1 | |
| SCHEMBL655951 | 0.89 | PI4KB (0.53) | PI4KBALDH1A1MAPTNPSR1MAPK1 | |
| SCHEMBL655575 | 0.88 | PI4KB (0.56) | PI4KBALDH1A1MAPTMAPK1CHIA | |
| SCHEMBL655387 | 0.88 | PI4KB (0.53) | PI4KBALDH1A1MAPTNPSR1MAPK1 | |
| SCHEMBL1721353 | 0.86 | PI4KB (0.51) | PI4KBALDH1A1MAPTNPSR1MAPK1 | |
| SCHEMBL653995 | 0.86 | PI4KB (0.52) | PI4KBCNR1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL655043 | 0.86 | PI4KB (0.53) | PI4KBALDH1A1MAPTNPSR1MAPK1 | |
| SCHEMBL655565 | 0.86 | PI4KB (0.53) | PI4KBALDH1A1MAPTNPSR1MAPK1 | |
| SCHEMBL654600 | 0.86 | PI4KB (0.52) | PI4KBALDH1A1MAPTNPSR1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2405973-A2 | THIAZOLOPYRIMIDINE MODULATORS AS IMMUNOSUPPRESSIVE AGENTS | Katholieke Universiteit Leuven, K.U. Leuven R&D (BE) | 2012-01-18 | — | — | EP | disclosed |