Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTH1R | Q03431 | 6/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13555084 | 0.91 | PTH1R (0.48) | PTH1R | |
| SCHEMBL13555108 | 0.90 | PTH1R (0.50) | PTH1R | |
| SCHEMBL16302358 | 0.87 | PTH1R (0.53) | PTH1R | |
| SCHEMBL16358610 | 0.86 | PTH1R (0.51) | PTH1R | |
| SCHEMBL879957 | 0.85 | PTH1R (0.46) | PTH1R | |
| SCHEMBL848490 | 0.84 | PTH1R (0.50) | PTH1R | |
| SCHEMBL848489 | 0.84 | PTH1R (0.50) | PTH1R | |
| SCHEMBL851192 | 0.84 | PTH1R (0.53) | PTH1R | |
| SCHEMBL850555 | 0.84 | PTH1R (0.53) | PTH1R | |
| SCHEMBL851193 | 0.84 | PTH1R (0.53) | PTH1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9487517-B2 | Spiroimidazolone derivative | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2016-11-08 | — | — | US | disclosed |
| US-9169254-B2 | Spiroimidazolone derivative | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2015-10-27 | — | — | US | disclosed |