SCHEMBL17209158

SCHEMBL17209158

c1ccc2c(c1)Cc1cc(-n3c4ccc(-c5ccc(-c6ccc(-c7cccc8ccccc78)cc6)cc5)cc4c4cc(-c5ccc(-c6ccc(-c7cccc8ccccc78)cc6)cc5)ccc43)ccc1-2

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALK Q9UM73 1/20 0.40
CA12 O43570 3/20 0.39
CA1 P00915 3/20 0.39
CA2 P00918 3/20 0.39
CA9 Q16790 3/20 0.39
CTDSP1 Q9GZU7 1/20 0.36
KDM4E B2RXH2 1/20 0.35
NPC1 O15118 1/20 0.35
ALDH1A1 P00352 1/20 0.35
LMNA P02545 1/20 0.35
MAPT P10636 1/20 0.35
HPGD P15428 1/20 0.35
RAB9A P51151 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
CNR1 P21554 1/20 0.33
MMP12 P39900 1/20 0.33
MMP13 P45452 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
PRKDC P78527 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17209276 1.00 ALK (0.40) ALKCA12CA1CA2CA9
SCHEMBL17209174 0.95 ALK (0.40) ALKCA12CA1CA2CA9
SCHEMBL17209218 0.95 ALK (0.40) ALKCA12CA1CA2CA9
SCHEMBL17209258 0.95 CTDSP1 (0.37) ALKCA12CA1CA2CA9
SCHEMBL17209246 0.94 CA12 (0.41) ALKCA12CA1CA2CA9
SCHEMBL17209165 0.94 CA12 (0.41) ALKCA12CA1CA2CA9
SCHEMBL17209227 0.94 CA12 (0.41) ALKCA12CA1CA2CA9
SCHEMBL17209137 0.94 CA12 (0.41) ALKCA12CA1CA2CA9
SCHEMBL17209250 0.92 CA12 (0.38) ALKCA12CA1CA2CA9
SCHEMBL17209138 0.92 CA12 (0.38) ALKCA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015163584-A1 NOVEL COMPOUND AND LIGHT EMITTING ELEMENT COMPRISING SAME 주식회사 엘엠에스 2015-10-29 WO disclosed