Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 20/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL524147 | 0.77 | SYK (0.57) | SYK | |
| SCHEMBL526640 | 0.71 | SYK (0.64) | SYK | |
| SCHEMBL523765 | 0.71 | SYK (0.64) | SYK | |
| SCHEMBL17210755 | 0.69 | SYK (0.60) | SYK | |
| SCHEMBL524244 | 0.68 | SYK (0.60) | SYK | |
| SCHEMBL523752 | 0.67 | SYK (0.57) | SYK | |
| SCHEMBL524437 | 0.67 | SYK (0.51) | SYK | |
| SCHEMBL14659234 | 0.67 | SYK (1.00) | SYK | |
| SCHEMBL373979 | 0.65 | SYK (0.74) | SYK | |
| SCHEMBL524016 | 0.65 | NPC1 (0.66) | SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2528915-B1 | SUBSTITUTED NAPHTHYRIDINES AND THEIR USE AS SYK KINASE INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2015-10-28 | — | — | EP | disclosed |