⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3348301 | 0.78 | — | — | |
| SCHEMBL3121766 | 0.75 | — | — | |
| SCHEMBL5323960 | 0.70 | — | — | |
| SCHEMBL290757 | 0.70 | — | — | |
| SCHEMBL1555131 | 0.67 | — | — | |
| SCHEMBL7178562 | 0.65 | GSK3A (0.50) | — | |
| SCHEMBL7638036 | 0.63 | — | — | |
| SCHEMBL6364430 | 0.60 | — | — | |
| SCHEMBL11376825 | 0.60 | TRIM24 (0.31) | — | |
| SCHEMBL133712 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 171 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230372310-A1 | Flavi-Block: A Pan-Flavivirus Inhibitor | BADEN-WÜRTTEMBERG STIFTUNG GMBH (DE) | 2023-11-23 | — | — | US | claimed |
| EP-4228631-A1 | FLAVI-BLOCK: A PAN-FLAVIVIRUS INHIBITOR | Baden-Württemberg Stiftung gGmbH (DE) | 2023-08-23 | — | — | EP | claimed |
| US-20230219978-A1 | COMPOUND HAVING MACROCYCLIC STRUCTURE AND USE THEREOF | SCINNOHUB PHARMACEUTICAL CO., LTD (CN) | 2023-07-13 | — | — | US | claimed |
| EP-4163283-A1 | COMPOUND HAVING MACROCYCLIC STRUCTURE AND USE THEREOF | Scinnohub Pharmaceutical Co., Ltd (CN) | 2023-04-12 | — | — | EP | claimed |
| CN-113754682-B | Compound having macrocyclic structure and use thereof | 赛诺哈勃药业（成都）有限公司 | 2023-01-06 | — | — | CN | claimed |
| WO-2022078602-A1 | FLAVI-BLOCK: A PAN-FLAVIVIRUS INHIBITOR | BADEN-WÜRTTEMBERG STIFTUNG GGMBH (DE) | 2022-04-21 | — | — | WO | claimed |
| CN-110407839-B | Preparation and application of triazole heterocyclic compound containing heteroaryl amide structure | 江西科技师范大学 | 2022-01-04 | — | — | CN | claimed |
| CN-113754682-A | Compounds having macrocyclic structure and uses thereof | 成都倍特药业股份有限公司 | 2021-12-07 | — | — | CN | claimed |
| WO-2021104529-A1 | MACROLIDE BREFELDIN A ESTER DERIVATIVE, AND USE | 中国海洋大学 | 2021-06-03 | — | — | WO | claimed |
| US-20190194166-A1 | SUBSTITUTED PYRIDINES AS INHIBITORS OF DNMT1 | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2019-06-27 | — | — | US | claimed |
| EP-0793499-A1 | METHOD AND COMPOSITION FOR REDUCING TUMOR DEVELOPMENT WITH A COMBINATION OF A TAXANE COMPOUND AND A TELLURIUM AND/OR SELENIUM COMPOUND | BAKER NORTON PHARMACEUTICALS, INC. (US) | 1997-09-10 | — | — | EP | claimed |
| US-5648486-A | LIPOXYGENASE INHIBITORS | CYTOMED, INC. (US) | 1997-07-15 | — | — | US | claimed |
| US-5530141-A | REDUCES THE CHEMOTAXIS AND RESPIRATORY BURST LEADING TO THE FORMATION OF DAMAGING OXYGEN RADICAL DURING INFLAMMATORY AND IMMUNE RESPONSE | CENTER FOR INNOVATIVE TECHNOLOGY (US) | 1996-06-25 | — | — | US | claimed |
| WO-1996018401-A1 | METHOD AND COMPOSITION FOR REDUCING TUMOR DEVELOPMENT WITH A COMBINATION OF A TAXANE COMPOUND AND A TELLURIUM AND/OR SELENIUM COMPOUND | BAKER NORTON PHARMACEUTICALS, INC. (US) | 1996-06-20 | — | — | WO | claimed |
| US-5434151-A | Treatment of immune and inflammatory disorders, aryl substituted tetrahydrofurans, tetrahydrothiophenes, cyclopentanes, pyrrolidines | CYTOMED, INC. (US) | 1995-07-18 | — | — | US | claimed |
| US-5384066-A | Free of nitriles, high holding ration (HR), liquid crystals | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-01-24 | — | — | US | claimed |
| US-5360711-A | COLORFASTNESS, RESISTANCE TO DISCOLORATION | FUJI PHOTO FILM CO., LTD. (JP) | 1994-11-01 | — | — | US | claimed |
| US-5358938-A | 2,5-Diaryl tetrahydrofurans, tetrahydrothiophenes, 1,3-cyclo-pentanes and pyrrolidines | CYTOMED, INC. (US) | 1994-10-25 | — | — | US | claimed |
| EP-0400971-A2 | Method for preparation of taxol | FLORIDA STATE UNIVERSITY (US) | 1990-12-05 | — | — | EP | claimed |
| EP-0365089-A2 | 2-Aryl-5(3-methoxy-5-(hydroxypropylsulfonyl)-4-propoxyphenyl) tetrahydrothiophen and analogs | MERCK & CO. INC. (US) | 1990-04-25 | — | — | EP | claimed |