⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1106445 | 0.73 | — | — | |
| SCHEMBL22756183 | 0.71 | TSHR (0.32) | — | |
| SCHEMBL13595534 | 0.69 | — | — | |
| SCHEMBL15471203 | 0.69 | KDM4E (0.38) | — | |
| SCHEMBL10312579 | 0.69 | CHRM2 (0.42) | — | |
| SCHEMBL23761859 | 0.67 | CHRM2 (0.52) | — | |
| SCHEMBL14350170 | 0.67 | — | — | |
| SCHEMBL21310486 | 0.67 | CYP2D6 (0.30) | — | |
| SCHEMBL24170710 | 0.67 | — | — | |
| SCHEMBL16368787 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12018093-B2 | Hemiasterlin derivatives and antibody-drug conjugates including same | Sumitomo Pharma Co., Ltd. (JP) | 2024-06-25 | — | — | US | disclosed |
| US-11110050-B2 | Hair styling method and kit thereof | WELLA OPERATIONS US, LLC (US) | 2021-09-07 | — | — | US | disclosed |
| US-11052035-B2 | Hair treatment method and kit thereof | WELLA OPERATIONS US, LLC (US) | 2021-07-06 | — | — | US | disclosed |
| US-20200247845-A1 | Hemiasterlin Derivatives and Antibody-Drug Conjugates Including Same | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2020-08-06 | — | — | US | disclosed |
| US-20190117550-A1 | HAIR TREATMENT METHOD AND KIT THEREOF | WELLA OPERATIONS US, LLC | 2019-04-25 | — | — | US | disclosed |
| US-10227340-B2 | Thiazolyl- or thiadiazolyl-substituted pyridyl compounds useful as kinase inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2019-03-12 | — | — | US | disclosed |
| US-20180072712-A1 | THIAZOLYL- OR THIADIAZOLYL-SUBSTITUTED PYRIDYL COMPOUNDS USEFUL AS KINASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2018-03-15 | — | — | US | disclosed |
| US-9872918-B2 | Hydroxyl-polymer-drug-protein conjugates | MERSANA THERAPEUTICS, INC. (US) | 2018-01-23 | — | — | US | disclosed |
| US-20150306240-A1 | HYDROXYL-POLYMER-DRUG-PROTEIN CONJUGATES | MERSANA THERAPEUTICS, INC. | 2015-10-29 | — | — | US | disclosed |