Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KB | Q9UBF8 | 8/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.47 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL653637 | 0.96 | PI4KB (0.53) | PI4KBKCNH2CHIAPPARGNR2E3 | |
| SCHEMBL654434 | 0.96 | PI4KB (0.54) | PI4KBKCNH2CYP3A4MAPTL3MBTL1 | |
| SCHEMBL653219 | 0.89 | PI4KB (0.53) | PI4KBKCNH2CHIAPPARGNR2E3 | |
| SCHEMBL655043 | 0.89 | PI4KB (0.53) | PI4KBKCNH2CYP3A4MAPTL3MBTL1 | |
| SCHEMBL655565 | 0.89 | PI4KB (0.53) | PI4KBKCNH2CHIACYP3A4PPARG | |
| SCHEMBL654589 | 0.88 | PI4KB (0.65) | PI4KBKCNH2MAPTKMT2AALDH1A1 | |
| SCHEMBL654877 | 0.88 | PI4KB (0.52) | PI4KBKCNH2CYP3A4MAPTL3MBTL1 | |
| SCHEMBL655116 | 0.88 | PI4KB (0.52) | PI4KBKCNH2CYP3A4MAPTL3MBTL1 | |
| SCHEMBL654372 | 0.86 | PI4KB (0.64) | PI4KBKCNH2CHIACYP3A4PPARG | |
| SCHEMBL1721353 | 0.86 | PI4KB (0.51) | PI4KBKCNH2CHIACYP3A4PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2575969-A1 | ANTIVIRAL ACTIVITY OF NOVEL BICYCLIC HETEROCYCLES | Katholieke Universiteit Leuven, K.U. Leuven R&D (BE) | 2013-04-10 | — | — | EP | claimed |
| EP-2405973-A2 | THIAZOLOPYRIMIDINE MODULATORS AS IMMUNOSUPPRESSIVE AGENTS | Katholieke Universiteit Leuven, K.U. Leuven R&D (BE) | 2012-01-18 | — | — | EP | disclosed |