SCHEMBL17211583

SCHEMBL17211583

C=CC(=O)OCCN(CCC)C(C)=O

nearest known ligand 0.55

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.55
HPGD P15428 1/20 0.55
ALDH1A1 P00352 4/20 0.46
TP53 P04637 3/20 0.46
HIF1A Q16665 3/20 0.46
CYP3A4 P08684 2/20 0.46
HSD17B10 Q99714 1/20 0.46
THRB P10828 4/20 0.42
ATM Q13315 1/20 0.40
HCAR2 Q8TDS4 4/20 0.38
ZDHHC20 Q5W0Z9 1/20 0.35
CA12 O43570 1/20 0.34
CA2 P00918 1/20 0.34
CA9 Q16790 1/20 0.34
MAPK1 P28482 2/20 0.34
SMN1; SMN2 Q16637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6062137 0.93 TSHR (0.52) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL27785329 0.88 TSHR (0.52) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL28542028 0.85 TSHR (0.53) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL21119730 0.80 TSHR (0.60) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL345655 0.80 TSHR (0.60) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL11310515 0.79 TSHR (0.58) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL17211578 0.79 TSHR (0.39) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL8547550 0.77 TP53 (0.64) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL17522086 0.77 TSHR (0.52) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL26487463 0.77 TSHR (0.53) TSHRHPGDALDH1A1TP53THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170291992-A1 REACTIVE POLYOXAZOLINES HAVING A PERFLUORINATED GROUP 3M INNOVATIVE PROPERTIES CO (US) 2017-10-12 US disclosed
US-9556340-B2 Polyoxazoline copolymers 3M INNOVATIVE PROPERTIES COMPANY (US) 2017-01-31 US disclosed
US-20150307718-A1 POLYOXAZOLINE COPOLYMERS SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2015-10-29 US disclosed