Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | LAP3 | P28838 | 6/20 | 0.33 |
| ▸ | ANPEP | P15144 | 4/20 | 0.33 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LPAR3 | Q9UBY5 | 5/20 | 0.31 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.31 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.31 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12212661 | 1.00 | CYP3A4 (0.40) | CYP3A4TSHRLAP3ANPEPERAP1 | |
| SCHEMBL17211777 | 1.00 | CYP3A4 (0.40) | CYP3A4TSHRLAP3ANPEPERAP1 | |
| SCHEMBL12212674 | 1.00 | CYP3A4 (0.40) | CYP3A4TSHRLAP3ANPEPERAP1 | |
| SCHEMBL12236054 | 0.92 | SAT1 (0.37) | CYP3A4TSHRLAP3 | |
| SCHEMBL26031762 | 0.90 | CYP3A4 (0.34) | CYP3A4TSHRALDH1A1 | |
| SCHEMBL17211785 | 0.88 | CYP3A4 (0.37) | CYP3A4TSHRALDH1A1 | |
| SCHEMBL17032647 | 0.85 | LPAR3 (0.52) | CYP3A4TSHRMEN1KMT2ALPAR3 | |
| SCHEMBL17032640 | 0.85 | LPAR3 (0.52) | CYP3A4TSHRMEN1KMT2ALPAR3 | |
| SCHEMBL17032654 | 0.85 | LPAR3 (0.52) | CYP3A4TSHRMEN1KMT2ALPAR3 | |
| SCHEMBL17032662 | 0.85 | LPAR3 (0.52) | CYP3A4TSHRMEN1KMT2ALPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2558578-B1 | COMPOSITIONS AND METHODS FOR INHIBITION OF NUCLEIC ACIDS FUNCTION | LIFE TECHNOLOGIES CORP (US) | 2015-10-28 | — | — | EP | disclosed |