⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10076786 | 1.00 | SMN1; SMN2 (0.60) | — | |
| SCHEMBL1703385 | 0.92 | SMN1; SMN2 (0.58) | — | |
| SCHEMBL12375164 | 0.92 | SMN1; SMN2 (0.58) | — | |
| SCHEMBL13293271 | 0.91 | MEN1 (0.53) | — | |
| SCHEMBL13520308 | 0.91 | SMN1; SMN2 (0.53) | — | |
| SCHEMBL15199099 | 0.91 | MEN1 (0.53) | — | |
| SCHEMBL621042 | 0.91 | SMN1; SMN2 (0.53) | — | |
| SCHEMBL14542248 | 0.91 | MEN1 (0.53) | — | |
| SCHEMBL19388000 | 0.91 | SMN1; SMN2 (0.53) | — | |
| SCHEMBL26964823 | 0.91 | SMN1; SMN2 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 169 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023205366-A1 | SMALL MOLECULE MODULATORS OF GP130 SIGNALING PATHWAYS | CARTHRONIX, INC. (US) | 2023-10-26 | — | — | WO | disclosed |
| US-11787788-B2 | Benzimidazole derivatives, and pharmaceutical compositions and methods of use thereof | CAPELLA THERAPEUTICS, INC. (US) | 2023-10-17 | — | — | US | disclosed |
| US-11780823-B2 | Indazole-3-carboxamides and their use as Wnt/β-catenin signaling pathway inhibitors | BIOSPLICE THERAPEUTICS, INC. (US) | 2023-10-10 | — | — | US | disclosed |
| US-20230286997-A1 | Compounds for the Treatment of Cancer and Inflammatory Disease | SHY Therapeutics LLC | 2023-09-14 | — | — | US | disclosed |
| WO-2023168291-A1 | COVALENT MODIFIERS OF AKT1 AND USES THEREOF | TERREMOTO BIOSCIENCES, INC. (US) | 2023-09-07 | — | — | WO | disclosed |
| US-20230265116-A1 | DEGRADATION OF (EGFR) BY CONJUGATION OF EGFR INHIBITORS WITH E3 LIGASE LIGAND AND METHODS OF USE | BEONE MEDICINES I GMBH (CH) | 2023-08-24 | — | — | US | disclosed |
| US-20230248834-A1 | DEGRADATION OF (EGFR) BY CONJUGATION OF EGFR INHIBITORS WITH E3 LIGASE LIGAND AND METHODS OF USE | BEONE MEDICINES I GMBH (CH) | 2023-08-10 | — | — | US | disclosed |
| US-20230242546-A1 | SUBSTITUTED PYRIDINES, PYRIDAZINES, PYRIMIDINES, AND 1,2,4-TRIAZINES AS TYK2 INHIBITORS | SUDO BIOSCIENCES LIMITED (GB) | 2023-08-03 | — | — | US | disclosed |
| US-20230212152-A1 | INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF | Pardes Biosciences, Inc. | 2023-07-06 | — | — | US | disclosed |
| US-20230212164-A1 | ANNULATED 2-AMINO-3-CYANO THIOPHENES AND DERIVATIVES FOR THE TREATMENT OF CANCER | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2023-07-06 | — | — | US | disclosed |
| US-20070105855-A1 | NOVEL HETEROCYCLIC COMPOUNDS USEFUL FOR THE TREATMENT OF INFLAMMATORY AND ALLERGIC DISORDERS: PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS S.A. (CH) | 2007-05-10 | — | — | US | disclosed |
| US-20070105855-A1 | NOVEL HETEROCYCLIC COMPOUNDS USEFUL FOR THE TREATMENT OF INFLAMMATORY AND ALLERGIC DISORDERS: PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS S.A. (CH) | 2007-05-10 | — | — | US | disclosed |
| CN-1060914-C | Fungicidal and insecticidal composition | BAYER AGROCHEM KK (JP) | 2001-01-24 | — | — | CN | disclosed |
| CN-1034982-C | fungicide and insecticide composition | BAYER AGROCHEM KK (JP) | 1997-05-28 | — | — | CN | disclosed |
| CN-1147336-A | Fungicidal and insecticidal composition | BAYER AGROCHEM KK (JP) | 1997-04-16 | — | — | CN | disclosed |
| CN-1137859-A | Fungicidal and insecticidal composition | BAYER AGROCHEM KK (JP) | 1996-12-18 | — | — | CN | disclosed |
| CN-1137860-A | Fugicial and insecticidal composition | BAYER AGROCHEM KK (JP) | 1996-12-18 | — | — | CN | disclosed |
| CN-1032040-C | Mixed fungicidal and insecticidal composition | BAYER AGROCHEM KK (JP) | 1996-06-19 | — | — | CN | disclosed |
| US-5521145-A | Iminothiazoline derivatives and herbicides containing them as active ingredients | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| EP-0683160-A1 | Iminothiazoline derivatives and herbicides containing them as active ingredients | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-11-22 | — | — | EP | disclosed |