Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 20/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL125508 | 0.95 | ELANE (0.59) | ELANE | |
| SCHEMBL3722875 | 0.86 | ELANE (0.67) | ELANE | |
| SCHEMBL3719709 | 0.86 | ELANE (0.67) | ELANE | |
| SCHEMBL15473086 | 0.85 | ELANE (0.45) | ELANE | |
| SCHEMBL124738 | 0.83 | ELANE (0.62) | ELANE | |
| SCHEMBL172183 | 0.79 | ELANE (0.70) | ELANE | |
| SCHEMBL122839 | 0.79 | ELANE (0.69) | ELANE | |
| SCHEMBL170099 | 0.78 | ELANE (0.69) | ELANE | |
| SCHEMBL18086853 | 0.78 | ELANE (0.69) | ELANE | |
| SCHEMBL18086836 | 0.78 | ELANE (0.78) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2234985-B1 | 4-(4-CYANO-2-THIOARYL)DIHYDROPYRIMIDINONES AND USE THEREOF | Bayer Pharma AG (DE) | 2012-03-07 | — | — | EP | disclosed |