Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 8/20 | 0.56 |
| ▸ | DRD2 | P14416 | 6/20 | 0.56 |
| ▸ | HTR2A | P28223 | 5/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13630510 | 0.90 | DRD3 (0.51) | DRD3DRD2HTR2ACHRM4 | |
| SCHEMBL4489334 | 0.90 | DRD3 (0.65) | DRD3DRD2HTR2A | |
| SCHEMBL4490968 | 0.90 | DRD3 (0.51) | DRD3DRD2HTR2ACHRM4 | |
| SCHEMBL13630513 | 0.90 | DRD3 (0.65) | DRD3DRD2HTR2A | |
| SCHEMBL4480402 | 0.87 | DRD3 (0.69) | DRD3DRD2HTR2A | |
| SCHEMBL13630511 | 0.87 | DRD3 (0.69) | DRD3DRD2HTR2A | |
| SCHEMBL4476770 | 0.86 | DRD3 (0.56) | DRD3DRD2HTR2ACHRM4 | |
| SCHEMBL13630508 | 0.86 | DRD3 (0.56) | DRD3DRD2HTR2ACHRM4 | |
| SCHEMBL17226567 | 0.86 | DRD3 (0.56) | DRD3DRD2HTR2ACHRM4 | |
| SCHEMBL13630030 | 0.85 | DRD3 (0.69) | DRD3DRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2038268-B1 | CARBONYLATED (AZA)CYCLOHEXANES AS DOPAMINE D3 RECEPTOR LIGANDS | BIOPROJET SOC CIV (FR) | 2015-11-04 | — | — | EP | claimed |