Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.38 |
| ▸ | HTR3B | O95264 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.38 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL795723 | 0.85 | MAPT (0.56) | MAPTLMNATSHRSMN1; SMN2ADORA2A | |
| SCHEMBL17220379 | 0.84 | MAPT (0.55) | MAPTLMNATSHRSMN1; SMN2ADORA2A | |
| SCHEMBL17220093 | 0.83 | MAPT (0.52) | MAPTLMNATSHRSMN1; SMN2CRHBP | |
| SCHEMBL796039 | 0.83 | MAPT (0.72) | MAPTLMNATSHRSMN1; SMN2CTSK | |
| SCHEMBL17220463 | 0.82 | MAPT (0.52) | MAPTLMNATSHRSMN1; SMN2ADORA2A | |
| SCHEMBL15100699 | 0.82 | RECQL (0.47) | MAPTTSHRSMN1; SMN2NPSR1HTR3E | |
| SCHEMBL17220240 | 0.81 | MAPT (0.51) | MAPTLMNATSHRSMN1; SMN2CTSS | |
| SCHEMBL17220005 | 0.76 | TSHR (0.54) | MAPTLMNATSHRSMN1; SMN2ADORA2A | |
| SCHEMBL17220217 | 0.76 | MAPT (0.54) | MAPTLMNATSHRSMN1; SMN2ADORA2A | |
| SCHEMBL17220458 | 0.75 | MAPT (0.52) | MAPTLMNATSHRSMN1; SMN2ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2616465-B1 | TRIAZINE-OXADIAZOLES | NOVARTIS AG (CH) | 2015-11-04 | — | — | EP | disclosed |