Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 12/20 | 0.42 |
| ▸ | F10 | P00742 | 7/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 7/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 7/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 7/20 | 0.38 |
| ▸ | F12 | P00748 | 6/20 | 0.37 |
| ▸ | F7 | P08709 | 6/20 | 0.37 |
| ▸ | F9 | P00740 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL17221932 | 0.77 | F2 (0.36) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL6924463 | 0.76 | F2 (0.36) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL6924800 | 0.76 | F2 (0.41) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL6924250 | 0.75 | F2 (0.47) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL6924283 | 0.74 | F2 (0.36) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL6921526 | 0.73 | F2 (0.47) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL6926517 | 0.73 | F2 (0.49) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL6924535 | 0.73 | F2 (0.41) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL6923244 | 0.72 | F2 (0.46) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL6926522 | 0.72 | F2 (0.47) | F2F10PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150315141-A1 | Thrombin Inhibitors | MERCK SHARP & DOHME CORP. (US) | 2015-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150315141-A1 | Thrombin Inhibitors | F3, F2, F9 | F2 2/4885F10 24/4885PRSS1 766/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.