SCHEMBL17225166

SCHEMBL17225166

CCCCC1CCC(c2ccc(C#Cc3ccc(N=C=S)c(F)c3)cc2)CC1

nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.35
MAPK1 P28482 1/20 0.35
KMT2A Q03164 1/20 0.35
CYP2C9 P11712 1/20 0.34
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
RAB9A P51151 1/20 0.31
ESR2 Q92731 1/20 0.30
SPHK1 Q9NYA1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20780018 0.97 MEN1 (0.34) MEN1MAPK1KMT2ACYP2C9ALDH1A1
SCHEMBL26941819 0.94 MEN1 (0.41) MEN1MAPK1KMT2ACYP2C9ALDH1A1
SCHEMBL26941817 0.89 ACACB (0.31) MEN1MAPK1KMT2A
SCHEMBL10348107 0.89 MAPK1 (0.36) MEN1MAPK1KMT2ACYP2C9ALDH1A1
SCHEMBL21577523 0.88 MEN1 (0.36) MEN1MAPK1KMT2ACYP2C9ALDH1A1
SCHEMBL25056666 0.88 MEN1 (0.36) MEN1MAPK1KMT2ACYP2C9ALDH1A1
SCHEMBL29305993 0.87 FFAR1 (0.30)
SCHEMBL26941851 0.87 MEN1 (0.36) MEN1MAPK1KMT2ACYP2C9ALDH1A1
SCHEMBL23051712 0.87 ESR1 (0.30) CYP2C9ESR2
SCHEMBL29165244 0.86 MEN1 (0.33) MEN1MAPK1KMT2ACYP2C9ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240228878-A1 COMPOUND, LIQUID CRYSTAL COMPOSITION, AS WELL AS LIQUID CRYSTAL DISPLAY ELEMENT, SENSOR, LIQUID CRYSTAL LENS, OPTICAL COMMUNICATION EQUIPMENT, AND ANTENNA EACH USING THE SAME DIC CORPORATION (JP) 2024-07-11 US disclosed
US-20240228878-A1 COMPOUND, LIQUID CRYSTAL COMPOSITION, AS WELL AS LIQUID CRYSTAL DISPLAY ELEMENT, SENSOR, LIQUID CRYSTAL LENS, OPTICAL COMMUNICATION EQUIPMENT, AND ANTENNA EACH USING THE SAME DIC CORPORATION (JP) 2024-07-11 US disclosed
US-20230400721-A1 METHOD FOR PRODUCING LIQUID CRYSTAL MATERIAL, METHOD FOR EVALUATING LIQUID CRYSTAL MATERIAL, MEASUREMENT APPARATUS THEREFOR, AND LIQUID CRYSTAL MATERIAL DIC CORPORATION (JP) 2023-12-14 US disclosed
US-20230400721-A1 METHOD FOR PRODUCING LIQUID CRYSTAL MATERIAL, METHOD FOR EVALUATING LIQUID CRYSTAL MATERIAL, MEASUREMENT APPARATUS THEREFOR, AND LIQUID CRYSTAL MATERIAL DIC CORPORATION (JP) 2023-12-14 US disclosed
US-20230313044-A1 COMPOUND, COMPOSITION, LIQUID CRYSTAL COMPOSITION, AND DEVICE DIC CORPORATION (JP) 2023-10-05 US disclosed
US-20230313044-A1 COMPOUND, COMPOSITION, LIQUID CRYSTAL COMPOSITION, AND DEVICE DIC CORPORATION (JP) 2023-10-05 US disclosed
US-10224620-B2 Antenna having radio frequency liquid crystal (RFLC) mixtures with high RF tuning, broad thermal operating ranges, and low viscosity KYMETA CORPORATION (US) 2019-03-05 US disclosed
EP-2799516-B1 LIQUID CRYSTAL MATERIAL OF SMECTIC PHASE IN HIGH SCATTERING STATE AND DISPLAY DEVICE THEREOF HALATION PHOTONICS CORP (CN) 2019-02-20 EP disclosed
US-9175220-B2 High scattering smectic liquid crystal material and display device using the same HALATION PHOTONICS CORPORATION (CN) 2015-11-03 US disclosed
US-9175220-B2 High scattering smectic liquid crystal material and display device using the same HALATION PHOTONICS CORPORATION (CN) 2015-11-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230313044-A1 COMPOUND, COMPOSITION, LIQUID CRYSTAL COMPOSITION, AND DEVICE NLK, TTI2, LBR MEN1 1839/4885MAPK1 562/4885KMT2A 4036/4885
US-20240228878-A1 COMPOUND, LIQUID CRYSTAL COMPOSITION, AS WELL AS LIQUID CRYSTAL DISPLAY ELEMENT, SENSOR, LIQUID CRYSTAL LENS, OPTICAL COMMUNICATION EQUIPMENT, AND ANTENNA EACH USING THE SAME TTI2, CCT4, CCT2 MEN1 2827/4885MAPK1 1226/4885KMT2A 3777/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.