Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 15/20 | 0.52 |
| ▸ | ESR1 | P03372 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.37 |
| ▸ | TUBB | P07437 | 1/20 | 0.37 |
| ▸ | YES1 | P07947 | 1/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.37 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.37 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.37 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.37 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.37 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.37 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17225369 | 0.79 | MAPT (0.41) | MEN1KMT2AKDM4EMAPTGSK3B | |
| SCHEMBL24306021 | 0.79 | TP53 (0.45) | MEN1KMT2AKDM1AKDM4EMAPT | |
| SCHEMBL9620277 | 0.79 | SMN1; SMN2 (0.41) | MEN1KMT2AKDM4ECYP3A4MAPT | |
| SCHEMBL4877147 | 0.78 | GAA (0.48) | MEN1KMT2AKDM1AKDM4ECYP3A4 | |
| SCHEMBL11971115 | 0.75 | DDB1 (0.41) | KMT2AKDM4ECYP19A1NPC1MAPT | |
| SCHEMBL1494248 | 0.75 | DDB1 (0.41) | KMT2AKDM4ECYP19A1NPC1MAPT | |
| SCHEMBL1494251 | 0.75 | DDB1 (0.41) | KMT2AKDM4ECYP19A1NPC1MAPT | |
| SCHEMBL11971110 | 0.75 | DDB1 (0.41) | KMT2AKDM4ECYP19A1NPC1MAPT | |
| SCHEMBL11971251 | 0.75 | MAP2K1 (0.53) | MEN1KMT2AKDM1ACYP19A1CYP3A4 | |
| SCHEMBL11971054 | 0.75 | MAP2K1 (0.53) | MEN1KMT2AKDM1ACYP19A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9174960-B2 | Compounds useful against kinetoplastideae parasites | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2015-11-03 | — | — | US | disclosed |