Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.68 |
| ▸ | PTPRF | P10586 | 1/20 | 0.68 |
| ▸ | IKBKB | O14920 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | CRHBP | P24387 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | PTPRA | P18433 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2157496 | 0.87 | MAPT (0.76) | IKBKBMAPTKDM4EALDH1A1LMNA | |
| SCHEMBL611492 | 0.86 | IKBKB (0.52) | PTPN1PTPRFIKBKBMAPTKDM4E | |
| SCHEMBL17226318 | 0.86 | PTPN1 (0.70) | PTPN1IKBKBMAPTKDM4EALDH1A1 | |
| SCHEMBL8239558 | 0.83 | PTPN1 (0.62) | PTPN1PTPRFIKBKBMAPTKDM4E | |
| SCHEMBL27653932 | 0.83 | PTPN1 (0.62) | PTPN1PTPRFIKBKBMAPTKDM4E | |
| SCHEMBL2455311 | 0.83 | PTPN1 (0.62) | PTPN1PTPRFIKBKBMAPTKDM4E | |
| SCHEMBL17226313 | 0.82 | IKBKB (0.52) | PTPN1PTPRFIKBKBMAPTKDM4E | |
| SCHEMBL3070348 | 0.82 | IKBKB (0.82) | PTPN1PTPRFIKBKBMAPTMEN1 | |
| SCHEMBL27610380 | 0.81 | NPSR1 (0.57) | PTPN1PTPRFIKBKBKDM4E | |
| SCHEMBL6317621 | 0.81 | PTPN1 (1.00) | PTPN1PTPRFIKBKBMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2403860-B1 | PHOSPHOTHIOPHENE AND PHOSPHOTHIAZOLE AS HCV POLYMERASE INHIBITORS | IDENIX PHARMACEUTICALS INC (US) | 2015-11-04 | — | — | EP | disclosed |