Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 9/20 | 0.55 |
| ▸ | CNR1 | P21554 | 6/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | BRD4 | O60885 | 5/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17227678 | 0.85 | BRD4 (0.62) | CNR2CNR1ALDH1A1BRD4HPGD | |
| SCHEMBL250298 | 0.81 | CNR2 (0.61) | CNR2CNR1BRD4LMNAMAPT | |
| SCHEMBL249640 | 0.81 | CNR2 (0.61) | CNR2CNR1ALDH1A1BRD4LMNA | |
| SCHEMBL252235 | 0.78 | CNR2 (0.58) | CNR2CNR1ALDH1A1BRD4LMNA | |
| SCHEMBL2736850 | 0.78 | CNR2 (0.60) | CNR2CNR1ALDH1A1BRD4HPGD | |
| SCHEMBL2736805 | 0.78 | CNR2 (0.58) | CNR2CNR1BRD4LMNAMAPT | |
| SCHEMBL2736842 | 0.77 | CNR2 (0.61) | CNR2CNR1ALDH1A1BRD4HPGD | |
| SCHEMBL2736810 | 0.77 | CNR2 (0.56) | CNR2CNR1BRD4LMNAMAPT | |
| SCHEMBL2736847 | 0.76 | CNR2 (0.58) | CNR2CNR1ALDH1A1BRD4HPGD | |
| SCHEMBL2736811 | 0.75 | CNR2 (0.54) | CNR2CNR1ALDH1A1BRD4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9643952-B2 | Pyridone compound | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2017-05-09 | — | — | US | disclosed |
| US-20150315172-A1 | PYRIDONE COMPOUND | KYOWA KIRIN CO., LTD. (JP) | 2015-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150315172-A1 | PYRIDONE COMPOUND | HRH4, HRH3, HRH1 | CNR2 851/4885CNR1 466/4885ALDH1A1 443/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.