Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18976382 | 1.00 | KCNH2 (0.36) | KCNH2SSTR4 | |
| SCHEMBL17751190 | 0.76 | KDM1A (0.33) | SSTR4 | |
| SCHEMBL18968286 | 0.76 | — | — | |
| SCHEMBL785780 | 0.76 | — | — | |
| SCHEMBL25692436 | 0.76 | — | — | |
| SCHEMBL24792230 | 0.73 | SSTR4 (0.30) | SSTR4 | |
| SCHEMBL27281663 | 0.73 | — | — | |
| SCHEMBL34474875 | 0.71 | SSTR4 (0.33) | SSTR4 | |
| SCHEMBL31208581 | 0.71 | SSTR4 (0.33) | SSTR4 | |
| SCHEMBL18969277 | 0.71 | SSTR4 (0.33) | SSTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3138843-A1 | ISOQUINOLINESULFONYL DERIVATIVE AS RHO KINASE INHIBITOR | Medshine Discovery Inc. (CN) | 2017-03-08 | — | — | EP | disclosed |
| WO-2015165341-A1 | ISOQUINOLINESULFONYL DERIVATIVE AS RHO KINASE INHIBITOR | 南京明德新药研发股份有限公司 | 2015-11-05 | — | — | WO | disclosed |