SCHEMBL17229095

SCHEMBL17229095

c1ccc2c(c1)ccc1ccc(-c3cc(-c4ccc5ncsc5c4)cc(-c4ccc5ncsc5c4)c3)cc12

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DYRK1A Q13627 1/20 0.57
RIPK1 Q13546 1/20 0.48
MAPK14 Q16539 1/20 0.44
ALDH1A1 P00352 2/20 0.43
HSD17B10 Q99714 2/20 0.43
APP P05067 1/20 0.42
TGFBR1 P36897 6/20 0.41
BMPR1A P36894 1/20 0.41
SMAD2 Q15796 1/20 0.41
RIPK2 O43353 1/20 0.40
RIPK3 Q9Y572 1/20 0.40
CYP3A4 P08684 1/20 0.40
PFKFB3 Q16875 2/20 0.40
HIF1A Q16665 1/20 0.39
CYP1B1 Q16678 1/20 0.39
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
LMNA P02545 1/20 0.39
MAPT P10636 1/20 0.39
RECQL P46063 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17691933 0.93 DYRK1A (0.56) DYRK1ARIPK1MAPK14ALDH1A1HSD17B10
SCHEMBL17691852 0.90 DYRK1A (0.55) DYRK1ARIPK1MAPK14ALDH1A1HSD17B10
SCHEMBL17691887 0.89 DYRK1A (0.51) DYRK1ARIPK1MAPK14ALDH1A1HSD17B10
SCHEMBL17691909 0.88 DYRK1A (0.54) DYRK1ARIPK1MAPK14ALDH1A1HSD17B10
SCHEMBL17231561 0.86 DYRK1A (0.58) DYRK1ARIPK1MAPK14ALDH1A1HSD17B10
SCHEMBL17231480 0.83 DYRK1A (0.57) DYRK1ARIPK1MAPK14ALDH1A1HSD17B10
SCHEMBL17231495 0.83 DYRK1A (0.57) DYRK1ARIPK1MAPK14ALDH1A1HSD17B10
SCHEMBL17231516 0.82 DYRK1A (0.53) DYRK1ARIPK1MAPK14ALDH1A1HSD17B10
SCHEMBL17231506 0.82 DYRK1A (0.53) DYRK1ARIPK1MAPK14ALDH1A1HSD17B10
SCHEMBL17691914 0.82 DYRK1A (0.56) DYRK1ARIPK1MAPK14ALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170148999-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD (KR) 2017-05-25 US disclosed
US-20170148999-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD (KR) 2017-05-25 US disclosed
US-9564598-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2017-02-07 US disclosed
US-9564598-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2017-02-07 US disclosed
US-20150318510-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD (KR) 2015-11-05 US disclosed
US-20150318510-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD (KR) 2015-11-05 US disclosed