Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 6/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1723676 | 1.00 | KCNH2 (0.47) | KCNH2 | |
| SCHEMBL1712326 | 0.91 | KCNH2 (0.40) | KCNH2 | |
| SCHEMBL3404974 | 0.83 | KCNH2 (0.41) | KCNH2 | |
| SCHEMBL15707719 | 0.82 | KCNH2 (0.37) | KCNH2 | |
| SCHEMBL2291676 | 0.81 | KCNH2 (0.48) | KCNH2 | |
| SCHEMBL1723454 | 0.81 | KCNH2 (0.48) | KCNH2 | |
| SCHEMBL1723413 | 0.81 | KCNH2 (0.38) | KCNH2 | |
| SCHEMBL1712766 | 0.79 | — | — | |
| SCHEMBL2289108 | 0.77 | — | — | |
| SCHEMBL2290332 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9822114-B2 | Tricyclic oxazolidinone antibiotic compounds | IDORSIA PHARMACEUTICALS LTD (CH) | 2017-11-21 | — | — | US | disclosed |
| US-20170029737-A1 | LUBRICANT COMPOSITIONS COMPRISING EPOXIDE COMPOUNDS | BASF SE (DE) | 2017-02-02 | — | — | US | disclosed |
| US-20160237088-A1 | TRICYCLIC OXAZOLIDINONE ANTIBIOTIC COMPOUNDS | IDORSIA PHARMACEUTICALS LTD (CH) | 2016-08-18 | — | — | US | disclosed |
| US-9410105-B2 | Lubricant compositions comprising epoxide compounds | BASF SE (DE) | 2016-08-09 | — | — | US | disclosed |
| US-9346804-B2 | Tricyclic oxazolidinone antibiotic compounds | ACTELION PHARMACEUTICALS LTD. (CH) | 2016-05-24 | — | — | US | disclosed |
| EP-2920284-A1 | LUBRICANT COMPOSITIONS COMPRISING EPOXIDE COMPOUNDS TO IMPROVE FLUOROPOLYMER SEAL COMPATIBILITY | BASF SE (DE) | 2015-09-23 | — | — | EP | disclosed |
| EP-2920285-A1 | LUBRICANT COMPOSITIONS COMPRISING EPOXIDE COMPOUNDS | BASF SE (DE) | 2015-09-23 | — | — | EP | disclosed |
| EP-2920286-A1 | LUBRICANT COMPOSITIONS COMPRISING EPOXIDE COMPOUNDS TO IMPROVE FLUOROPOLYMER SEAL COMPATIBILITY | BASF SE (DE) | 2015-09-23 | — | — | EP | disclosed |
| EP-2344495-B1 | TRICYCLIC OXAZOLIDINONE ANTIBIOTIC COMPOUNDS | ACTELION PHARMACEUTICALS LTD (CH) | 2014-12-31 | — | — | EP | disclosed |
| US-20140142093-A1 | TRICYCLIC OXAZOLIDINONE ANTIBIOTIC COMPOUNDS | ACTELION PHARMACEUTICALS LTD. (CH) | 2014-05-22 | — | — | US | disclosed |
| US-20140142011-A1 | Lubricant Compositions Comprising Epoxide Compounds | BASF SE | 2014-05-22 | — | — | US | disclosed |
| WO-2014078702-A1 | LUBRICANT COMPOSITIONS COMPRISING EPOXIDE COMPOUNDS TO IMPROVE FLUOROPOLYMER SEAL COMPATIBILITY | BASF SE (DE) | 2014-05-22 | — | — | WO | disclosed |
| US-20140142010-A1 | Lubricant Compositions Comprising Epoxide Compounds | BASF SE | 2014-05-22 | — | — | US | disclosed |
| US-20140142009-A1 | Lubricant Compositions Comprising Epoxide Compounds | BASF SE | 2014-05-22 | — | — | US | disclosed |
| WO-2014078691-A1 | LUBRICANT COMPOSITIONS COMPRISING EPOXIDE COMPOUNDS | BASF SE (DE) | 2014-05-22 | — | — | WO | disclosed |
| US-20140142008-A1 | Lubricant Compositions Comprising Epoxide Compounds | BASF SE | 2014-05-22 | — | — | US | disclosed |
| WO-2014078712-A1 | LUBRICANT COMPOSITIONS COMPRISING EPOXIDE COMPOUNDS TO IMPROVE FLUOROPOLYMER SEAL COMPATIBILITY | BASF SE (DE) | 2014-05-22 | — | — | WO | disclosed |
| EP-2344495-A1 | TRICYCLIC OXAZOLIDINONE ANTIBIOTIC COMPOUNDS | Actelion Pharmaceuticals Ltd. (CH) | 2011-07-20 | — | — | EP | disclosed |
| WO-2010041194-A1 | TRICYCLIC OXAZOLIDINONE ANTIBIOTIC COMPOUNDS | ACTELION PHARMACEUTICALS LTD (CH) | 2010-04-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160237088-A1 | TRICYCLIC OXAZOLIDINONE ANTIBIOTIC COMPOUNDS | H1-3, HRH3, HRH4 | KCNH2 206/4885 |
| US-20140142093-A1 | TRICYCLIC OXAZOLIDINONE ANTIBIOTIC COMPOUNDS | OXA1L, H1-3, NGLY1 | KCNH2 261/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.