Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 16/20 | 0.47 |
| ▸ | PIK3R1 | P27986 | 8/20 | 0.47 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.42 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17235287 | 1.00 | PIK3CD (0.47) | PIK3CDPIK3R1PIK3CBPIK3R2PIK3CA | |
| SCHEMBL17234956 | 1.00 | PIK3CD (0.47) | PIK3CDPIK3R1PIK3CBPIK3R2PIK3CA | |
| SCHEMBL17235378 | 0.91 | PIK3CD (0.49) | PIK3CDPIK3R1PIK3CBPIK3CAPIK3CG | |
| SCHEMBL17235047 | 0.91 | PIK3CD (0.49) | PIK3CDPIK3R1PIK3CBPIK3CAPIK3CG | |
| SCHEMBL17235201 | 0.91 | PIK3CD (0.49) | PIK3CDPIK3R1PIK3CBPIK3CAPIK3CG | |
| SCHEMBL17234953 | 0.91 | PIK3CD (0.51) | PIK3CDPIK3R1PIK3CBPIK3R2PIK3CA | |
| SCHEMBL17235379 | 0.91 | PIK3CD (0.51) | PIK3CDPIK3R1PIK3CBPIK3R2PIK3CA | |
| SCHEMBL17235162 | 0.91 | PIK3CD (0.51) | PIK3CDPIK3R1PIK3CBPIK3R2PIK3CA | |
| SCHEMBL17235336 | 0.90 | PIK3CD (0.51) | PIK3CDPIK3R1PIK3CBPIK3R2PIK3CA | |
| SCHEMBL17235290 | 0.90 | PIK3CD (0.51) | PIK3CDPIK3R1PIK3CBPIK3R2PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015168079-A1 | PYRIMIDINE OR PYRIDINE DERIVATIVES USEFUL AS PI3K INHIBITORS | INFINITY PHARMACEUTICALS, INC. (US) | 2015-11-05 | — | — | WO | disclosed |