Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 20/20 | 0.72 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.72 |
| ▸ | PIK3R2 | O00459 | 13/20 | 0.66 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17235650 | 0.99 | PIK3CD (0.71) | PIK3CDPIK3R1PIK3R2PIK3CG | |
| SCHEMBL17235572 | 0.97 | PIK3CD (0.72) | PIK3CDPIK3R1PIK3R2PIK3CG | |
| SCHEMBL17234999 | 0.97 | PIK3CD (0.72) | PIK3CDPIK3R1PIK3R2PIK3CG | |
| SCHEMBL17235624 | 0.97 | PIK3CD (0.72) | PIK3CDPIK3R1PIK3R2PIK3CG | |
| SCHEMBL17235645 | 0.87 | PIK3CD (0.78) | PIK3CDPIK3R1PIK3R2PIK3CG | |
| SCHEMBL17235340 | 0.87 | PIK3CD (0.78) | PIK3CDPIK3R1PIK3R2PIK3CG | |
| SCHEMBL17235190 | 0.87 | PIK3CD (0.78) | PIK3CDPIK3R1PIK3R2PIK3CG | |
| SCHEMBL14729926 | 0.85 | PIK3CD (0.59) | PIK3CDPIK3R1PIK3R2PIK3CG | |
| SCHEMBL17234984 | 0.85 | PIK3CD (0.77) | PIK3CDPIK3R1PIK3R2PIK3CG | |
| SCHEMBL14729953 | 0.85 | PIK3CD (0.58) | PIK3CDPIK3R1PIK3R2PIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015168079-A1 | PYRIMIDINE OR PYRIDINE DERIVATIVES USEFUL AS PI3K INHIBITORS | INFINITY PHARMACEUTICALS, INC. (US) | 2015-11-05 | — | — | WO | disclosed |