⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL513904 | 0.81 | — | — | |
| SCHEMBL2645242 | 0.69 | — | — | |
| SCHEMBL17996896 | 0.69 | — | — | |
| SCHEMBL10710808 | 0.56 | — | — | |
| SCHEMBL2728145 | 0.56 | — | — | |
| SCHEMBL14313875 | 0.55 | — | — | |
| SCHEMBL12003183 | 0.53 | — | — | |
| SCHEMBL9816003 | 0.53 | — | — | |
| SCHEMBL24637544 | 0.51 | — | — | |
| SCHEMBL60658 | 0.51 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3766882-B1 | PHTHALAZINE ISOXAZOLE ALKOXY DERIVATIVES, PREPARATION METHOD THEREOF, PHARMACEUTICAL COMPOSITION AND USE THEREOF | SHANGHAI SIMR BIOTECHNOLOGY CO LTD (CN) | 2023-08-23 | — | — | EP | claimed |
| EP-3661934-B1 | [1,2,4]TRIAZOLO[4,3-A]PYRIDINYL SUBSTITUTED INDOLE COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2022-06-01 | — | — | EP | claimed |
| EP-3209664-B1 | BICYCLIC HETEROARYL AMINE COMPOUNDS AS PI3K INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2020-06-03 | — | — | EP | claimed |
| EP-2970235-B1 | NOVEL INHIBITORS | PROBIODRUG AG (DE) | 2019-06-19 | — | — | EP | claimed |
| EP-3091013-B1 | 1-(3-AMINOPROPYL) SUBSTITUTED CYCLIC AMINE COMPOUNDS, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | SHANGHAI INST MATERIA MEDICA CAS (CN) | 2018-08-08 | — | — | EP | claimed |
| EP-2814822-B1 | NOVEL PYRROLIDINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2016-04-20 | — | — | EP | claimed |
| EP-2757103-B1 | PYRROLIDINE-3-YLACETIC ACID DERIVATIVE | EISAI R&D MAN CO LTD (JP) | 2016-01-06 | — | — | EP | claimed |
| EP-2230238-B1 | INDOLE AND INDAZOLE DERIVATIVES HAVING A CELL-, TISSUE- AND ORGAN-PRESERVING EFFECT | LG LIFE SCIENCES LTD (KR) | 2013-12-11 | — | — | EP | claimed |
| EP-2152712-B1 | AMINO-HETEROCYCLIC COMPOUNDS | PFIZER (US) | 2012-01-11 | — | — | EP | claimed |
| EP-0861235-B1 | SUBSTITUTED BENZYLAMINOPIPERIDINE COMPOUNDS | PFIZER (US) | 2001-11-07 | — | — | EP | claimed |
| EP-0138669-B1 | PROCESS FOR THE PREPARATION OF SILANES FROM METHYLDICHLOROSILANE AND CHLOROSILANES | RHONE-POULENC CHIMIE (FR) | 1988-08-10 | — | — | EP | claimed |
| EP-0138670-B1 | PROCESS FOR THE PREPARATION OF SILANES WITH A SI-H BOND BY REDISTRIBUTION | RHONE-POULENC CHIMIE (FR) | 1988-05-25 | — | — | EP | claimed |
| EP-0138669-A2 | Process for the preparation of silanes from methyldichlorosilane and chlorosilanes | RHONE-POULENC CHIMIE (FR) | 1985-04-24 | — | — | EP | claimed |
| EP-0138670-A2 | Process for the preparation of silanes with a Si-H bond by redistribution | RHONE-POULENC CHIMIE (FR) | 1985-04-24 | — | — | EP | claimed |
| EP-0138669-B1 | PROCESS FOR THE PREPARATION OF SILANES FROM METHYLDICHLOROSILANE AND CHLOROSILANES | RHONE-POULENC CHIMIE (FR) | 1988-08-10 | — | — | EP | disclosed |
| EP-0138670-B1 | PROCESS FOR THE PREPARATION OF SILANES WITH A SI-H BOND BY REDISTRIBUTION | RHONE-POULENC CHIMIE (FR) | 1988-05-25 | — | — | EP | disclosed |
| EP-0138669-A2 | Process for the preparation of silanes from methyldichlorosilane and chlorosilanes | RHONE-POULENC CHIMIE (FR) | 1985-04-24 | — | — | EP | disclosed |
| EP-0138670-A2 | Process for the preparation of silanes with a Si-H bond by redistribution | RHONE-POULENC CHIMIE (FR) | 1985-04-24 | — | — | EP | disclosed |