Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 12/20 | 0.80 |
| ▸ | TLR1 | Q15399 | 12/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MBD2 | Q9UBB5 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16692239 | 0.89 | TLR2 (1.00) | TLR2TLR1ALDH1A1LMNANPSR1 | |
| SCHEMBL17242583 | 0.87 | TLR2 (0.87) | TLR2TLR1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL17242638 | 0.87 | TLR2 (0.86) | TLR2TLR1MAPT | |
| SCHEMBL17243259 | 0.83 | TLR2 (0.89) | TLR2TLR1ALDH1A1LMNANPSR1 | |
| SCHEMBL17242564 | 0.82 | TLR2 (0.87) | TLR2TLR1ALDH1A1LMNANPSR1 | |
| SCHEMBL17242568 | 0.82 | TLR2 (0.78) | TLR2TLR1ALDH1A1LMNANPSR1 | |
| SCHEMBL17242602 | 0.82 | TLR2 (0.78) | TLR2TLR1ALDH1A1LMNANPSR1 | |
| SCHEMBL17242571 | 0.81 | TLR2 (0.80) | TLR2TLR1ALDH1A1PKMRAB9A | |
| SCHEMBL17243299 | 0.81 | TLR2 (0.83) | TLR2TLR1ALDH1A1LMNANPSR1 | |
| SCHEMBL17242494 | 0.81 | TLR2 (0.83) | TLR2TLR1ALDH1A1GAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015171951-A1 | 2-(4-ARYL-1H-IMIDAZOL-1-YL)ANILINE COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2015-11-12 | — | — | WO | disclosed |