Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLA1 | P09884 | 1/20 | 0.59 |
| ▸ | CYP46A1 | Q9Y6A2 | 2/20 | 0.58 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 2/20 | 0.54 |
| ▸ | OSBP | P22059 | 2/20 | 0.54 |
| ▸ | RORC | P51449 | 2/20 | 0.54 |
| ▸ | OSBP2 | Q969R2 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.54 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.53 |
| ▸ | NPC1L1 | Q9UHC9 | 5/20 | 0.52 |
| ▸ | GBA1 | P04062 | 2/20 | 0.52 |
| ▸ | UGCG | Q16739 | 2/20 | 0.52 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | CRYAB | P02511 | 1/20 | 0.49 |
| ▸ | HMGCR | P04035 | 1/20 | 0.49 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.49 |
| ▸ | ITGAV | P06756 | 1/20 | 0.49 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17244044 | 0.93 | POLA1 (0.62) | POLA1CYP46A1PLA2G2AUSP2OSBP | |
| SCHEMBL3155816 | 0.92 | POLA1 (0.61) | POLA1CYP46A1PLA2G2AUSP2OSBP | |
| SCHEMBL318235 | 0.92 | POLA1 (0.61) | POLA1CYP46A1PLA2G2AUSP2OSBP | |
| SCHEMBL3155812 | 0.92 | POLA1 (0.61) | POLA1CYP46A1PLA2G2AUSP2OSBP | |
| SCHEMBL9949176 | 0.92 | POLA1 (0.61) | POLA1CYP46A1PLA2G2AUSP2OSBP | |
| SCHEMBL318236 | 0.92 | POLA1 (0.61) | POLA1CYP46A1PLA2G2AUSP2OSBP | |
| SCHEMBL9949178 | 0.92 | POLA1 (0.61) | POLA1CYP46A1PLA2G2AUSP2OSBP | |
| SCHEMBL12990241 | 0.92 | POLA1 (0.61) | POLA1CYP46A1PLA2G2AUSP2OSBP | |
| SCHEMBL15007261 | 0.91 | POLA1 (0.60) | POLA1CYP46A1PLA2G2AUSP2OSBP | |
| SCHEMBL3514954 | 0.91 | POLA1 (0.60) | POLA1CYP46A1PLA2G2AUSP2OSBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9181305-B2 | Exendin-4 peptide analogues | SANOFI (FR) | 2015-11-10 | — | — | US | disclosed |