SCHEMBL17245497

SCHEMBL17245497

c1ccc(-n2c3ccccc3c3c4ccccc4c4c5ccccc5n(-c5ccc6cnccc6c5)c4c32)cc1

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ CYP19A1 P11511 1/20 0.42
▸ TOP2A P11388 1/20 0.40
▸ KDM4E B2RXH2 1/20 0.39
▸ ATM Q13315 1/20 0.39
▸ L3MBTL1 Q9Y468 1/20 0.39
▸ MKNK2 Q9HBH9 1/20 0.38
▸ CLK1 P49759 1/20 0.37
▸ TDO2 P48775 1/20 0.37
▸ IMPDH2 P12268 3/20 0.36
▸ MAPT P10636 1/20 0.35
▸ MAPK10 P53779 2/20 0.35
▸ MAPK9 P45984 1/20 0.35
▸ KCNH2 Q12809 1/20 0.35
▸ AOC3 Q16853 1/20 0.35
▸ GRM4 Q14833 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17245499 0.94 CYP19A1 (0.39) CYP19A1TOP2AKDM4EATML3MBTL1
SCHEMBL17705405 0.91 CYP19A1 (0.44) CYP19A1TOP2AKDM4EATML3MBTL1
SCHEMBL17245397 0.88 KDM4E (0.44) CYP19A1TOP2AKDM4EATML3MBTL1
SCHEMBL17705419 0.88 CYP19A1 (0.43) CYP19A1TOP2AKDM4EATML3MBTL1
SCHEMBL17245309 0.88 KDM4E (0.44) CYP19A1TOP2AKDM4EATML3MBTL1
SCHEMBL17245403 0.87 KDM4E (0.41) CYP19A1TOP2AKDM4EATML3MBTL1
SCHEMBL17245402 0.87 KDM4E (0.41) CYP19A1TOP2AKDM4EATML3MBTL1
SCHEMBL17989936 0.85 CYP19A1 (0.36) CYP19A1TOP2AKDM4EATML3MBTL1
SCHEMBL17427585 0.85 KDM4E (0.47) KDM4EATML3MBTL1MAPK10MAPK9
SCHEMBL17246204 0.83 CYP19A1 (0.37) CYP19A1TOP2AKDM4EMKNK2CLK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10573839-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2020-02-25 — — US disclosed
US-10020459-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2018-07-10 — — US disclosed
US-10020459-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2018-07-10 — — US disclosed
US-9818950-B2 Organic light-emitting devices SAMSUNG DISPLAY CO., LTD. (KR) 2017-11-14 — — US disclosed
US-9818950-B2 Organic light-emitting devices SAMSUNG DISPLAY CO., LTD. (KR) 2017-11-14 — — US disclosed
US-9748510-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2017-08-29 — — US disclosed
US-9748510-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2017-08-29 — — US disclosed
US-20160118590-A1 ORGANIC LIGHT-EMITTING DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2016-04-28 — — US disclosed
US-20160118590-A1 ORGANIC LIGHT-EMITTING DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2016-04-28 — — US disclosed
US-20150325801-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2015-11-12 — — US disclosed
US-20150325801-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2015-11-12 — — US disclosed
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