SCHEMBL17246773

SCHEMBL17246773

c1ccc2cc(-c3ccc(-c4c5ccccc5c(-c5ccc6ccccc6c5)c5cc(-c6ccc(-c7cnc8ccccc8c7)nc6)ccc45)cc3)ccc2c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIK3CA P42336 4/20 0.43
PIK3CD O00329 3/20 0.43
PDGFRB P09619 3/20 0.43
PDGFRA P16234 3/20 0.43
MTOR P42345 3/20 0.43
PIK3CB P42338 2/20 0.43
PIK3CG P48736 2/20 0.43
CYP2A6 P11509 1/20 0.41
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA9 Q16790 1/20 0.40
BIRC5 O15392 1/20 0.40
PRMT5 O14744 1/20 0.40
WDR77 Q9BQA1 1/20 0.40
TOP2A P11388 1/20 0.39
TOP2B Q02880 1/20 0.39
CYP17A1 P05093 1/20 0.38
CYP19A1 P11511 1/20 0.38
CYP11B1 P15538 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19374105 1.00 PIK3CA (0.43) PIK3CAPIK3CDPDGFRBPDGFRAMTOR
SCHEMBL13759448 0.99 PDGFRB (0.43) PIK3CAPIK3CDPDGFRBPDGFRAMTOR
SCHEMBL2601568 0.97 PIK3CA (0.44) PIK3CAPIK3CDPDGFRBPDGFRAMTOR
SCHEMBL13759489 0.95 PDGFRB (0.47) PIK3CAPIK3CDPDGFRBPDGFRAMTOR
SCHEMBL13759476 0.94 PIK3CD (0.47) PIK3CAPIK3CDPDGFRBPDGFRAMTOR
SCHEMBL13759464 0.93 CYP2A6 (0.46) PIK3CAPIK3CDPDGFRBPDGFRAMTOR
SCHEMBL13759495 0.90 BIRC5 (0.48) PIK3CAPIK3CDPDGFRBPDGFRAMTOR
SCHEMBL13759478 0.90 PDGFRB (0.45) PIK3CAPIK3CDPDGFRBPDGFRAMTOR
SCHEMBL17246769 0.90 PDGFRB (0.53) PIK3CAPIK3CDPDGFRBPDGFRAMTOR
SCHEMBL12571838 0.90 CYP11B1 (0.43) CYP17A1CYP19A1CYP11B1CYP11B2ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10833280-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2020-11-10 US disclosed
US-10333074-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2019-06-25 US disclosed
US-10020459-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2018-07-10 US disclosed
US-10020459-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2018-07-10 US disclosed
US-20170077412-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-03-16 US disclosed
US-20170077412-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-03-16 US disclosed
US-20150325801-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2015-11-12 US disclosed
US-20150325801-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2015-11-12 US disclosed