Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | MDM2 | Q00987 | 5/20 | 0.48 |
| ▸ | CPB1 | P15086 | 1/20 | 0.48 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.48 |
| ▸ | MDM4 | O15151 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.45 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30895549 | 1.00 | TLR2 (0.54) | TLR2KMT2AMDM2CPB1CPB2 | |
| SCHEMBL30895406 | 0.98 | TLR2 (0.52) | TLR2KMT2AMDM2CPB1CPB2 | |
| SCHEMBL29681768 | 0.93 | KMT2A (0.55) | TLR2KMT2AMDM2CPB1CPB2 | |
| SCHEMBL30895587 | 0.93 | KMT2A (0.52) | TLR2KMT2AMDM2MDM4TP53 | |
| SCHEMBL9933277 | 0.90 | HDAC1 (0.52) | TLR2KMT2ACPB1CPB2SIRT2 | |
| SCHEMBL9933279 | 0.90 | HDAC1 (0.52) | TLR2KMT2ACPB1CPB2SIRT2 | |
| SCHEMBL29445594 | 0.90 | KMT2A (0.59) | TLR2KMT2AMDM2CPB1CPB2 | |
| SCHEMBL30425443 | 0.90 | KMT2A (0.59) | TLR2KMT2AMDM2CPB1CPB2 | |
| SCHEMBL3624369 | 0.89 | TLR2 (0.58) | TLR2KMT2AMDM2MDM4TP53 | |
| SCHEMBL29466503 | 0.89 | TLR2 (0.58) | TLR2KMT2AMDM2MDM4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015171792-A1 | METAL/RADIOMETAL-LABELED PSMA INHIBITORS FOR PSMA-TARGETED IMAGING AND RADIOTHERAPY | THE JOHNS HOPKINS UNIVERSITY (US) | 2015-11-12 | — | — | WO | disclosed |