Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 6/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TLR2 | O60603 | 5/20 | 0.48 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.48 |
| ▸ | MDM4 | O15151 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2524769 | 0.93 | MDM2 (0.59) | MDM2KMT2ATLR2TLR1MDM4 | |
| SCHEMBL30783486 | 0.93 | MDM2 (0.59) | MDM2KMT2ATLR2TLR1MDM4 | |
| SCHEMBL29370147 | 0.93 | MDM2 (0.59) | MDM2KMT2ATLR2TLR1MDM4 | |
| SCHEMBL30886226 | 0.93 | MDM2 (0.59) | MDM2KMT2ATLR2TLR1MDM4 | |
| SCHEMBL29372236 | 0.93 | MDM2 (0.59) | MDM2KMT2ATLR2TLR1MDM4 | |
| SCHEMBL2292778 | 0.93 | MDM2 (0.59) | MDM2KMT2ATLR2TLR1MDM4 | |
| SCHEMBL1738182 | 0.93 | MDM2 (0.59) | MDM2KMT2ATLR2TLR1MDM4 | |
| SCHEMBL30895590 | 0.92 | MDM2 (0.55) | MDM2KMT2ATLR2TLR1 | |
| SCHEMBL9933933 | 0.92 | MDM2 (0.55) | MDM2KMT2ATLR2TLR1 | |
| SCHEMBL25357595 | 0.92 | MDM2 (0.58) | MDM2KMT2ATLR2TLR1MDM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015171792-A1 | METAL/RADIOMETAL-LABELED PSMA INHIBITORS FOR PSMA-TARGETED IMAGING AND RADIOTHERAPY | THE JOHNS HOPKINS UNIVERSITY (US) | 2015-11-12 | — | — | WO | disclosed |