Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.44 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9548214 | 0.87 | GAA (0.46) | EGLN1GRIA2GAAMAPTDRD2 | |
| SCHEMBL13534830 | 0.86 | CHRM3 (0.41) | CHRM3DRD2 | |
| SCHEMBL30543100 | 0.83 | EGLN1 (0.43) | EGLN1GRIA2GAAMAPT | |
| SCHEMBL16268692 | 0.83 | EGLN1 (0.43) | EGLN1GRIA2GAAMAPT | |
| SCHEMBL4478717 | 0.83 | EGLN1 (0.43) | EGLN1GRIA2GAAMAPT | |
| SCHEMBL31651974 | 0.83 | EGLN1 (0.43) | EGLN1GRIA2GAAMAPT | |
| SCHEMBL3429946 | 0.82 | KDM4E (0.53) | GAAMAPTCHRM3DRD2 | |
| Hydrochloric Acid SCHEMBL16267702 | 0.81 | EGLN1 (0.42) | EGLN1GRIA2GAAMAPT | |
| Hydrochloric Acid SCHEMBL32677117 | 0.81 | EGLN1 (0.42) | EGLN1GRIA2GAAMAPT | |
| Hydrochloric Acid SCHEMBL32677096 | 0.81 | EGLN1 (0.42) | EGLN1GRIA2GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3274361-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | Polyphor Ag (CH) | 2018-01-31 | — | — | EP | disclosed |
| WO-2016150576-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | POLYPHOR AG (CH) | 2016-09-29 | — | — | WO | disclosed |
| EP-2978772-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | Polyphor AG (CH) | 2016-02-03 | — | — | EP | disclosed |
| EP-2978771-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | Polyphor Ag (CH) | 2016-02-03 | — | — | EP | disclosed |
| EP-2897949-A1 | IAP ANTAGONISTS | Bristol-Myers Squibb Company (US) | 2015-07-29 | — | — | EP | disclosed |
| EP-2861581-A1 | IAP ANTAGONISTS | Bristol-Myers Squibb Company (US) | 2015-04-22 | — | — | EP | disclosed |
| WO-2014161782-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | POLYPHOR AG (CH) | 2014-10-09 | — | — | WO | disclosed |
| WO-2014161781-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | POLYPHOR AG (CH) | 2014-10-09 | — | — | WO | disclosed |
| WO-2014047024-A1 | IAP ANTAGONISTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2014-03-27 | — | — | WO | disclosed |
| WO-2013192286-A1 | IAP ANTAGONISTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2013-12-27 | — | — | WO | disclosed |
| EP-2406247-A1 | COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS | Prosidion Limited (GB) | 2012-01-18 | — | — | EP | disclosed |
| WO-2010103333-A1 | COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS | PROSIDION LIMITED (GB) | 2010-09-16 | — | — | WO | disclosed |
| EP-2200609-A1 | COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS | Prosidion Limited (GB) | 2010-06-30 | — | — | EP | disclosed |
| WO-2009034388-A1 | COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS | PROSIDION LIMITED (GB) | 2009-03-19 | — | — | WO | disclosed |