Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | TDO2 | P48775 | 2/20 | 0.41 |
| ▸ | CFD | P00746 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | GNRHR | P30968 | 1/20 | 0.38 |
| ▸ | BCDIN3D | Q7Z5W3 | 3/20 | 0.36 |
| ▸ | MC4R | P32245 | 3/20 | 0.36 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1728815 | 0.89 | IDO1 (0.39) | IDO1TDO2CFDGNRHRBCDIN3D | |
| SCHEMBL1727508 | 0.89 | IDO1 (0.39) | IDO1TDO2CFDGNRHRBCDIN3D | |
| SCHEMBL4672694 | 0.85 | IDO1 (0.44) | IDO1TDO2CFDGNRHRBCDIN3D | |
| SCHEMBL3680376 | 0.85 | AOC3 (0.38) | CFD | |
| SCHEMBL30682632 | 0.83 | IDO1 (0.40) | IDO1TDO2MC4RPSIP1CYP3A4 | |
| SCHEMBL30682733 | 0.83 | IDO1 (0.40) | IDO1TDO2MC4RPSIP1CYP3A4 | |
| SCHEMBL5205809 | 0.83 | IDO1 (0.40) | IDO1TDO2MC4RPSIP1CYP3A4 | |
| SCHEMBL1728822 | 0.83 | IDO1 (0.40) | IDO1TDO2MC4RPSIP1CYP3A4 | |
| SCHEMBL1727474 | 0.83 | IDO1 (0.40) | IDO1TDO2MC4RPSIP1CYP3A4 | |
| SCHEMBL30682588 | 0.83 | IDO1 (0.40) | IDO1TDO2MC4RPSIP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1255738-B1 | GONADOTROPIN-RELEASING HORMONE RECEPTOR ANTAGONISTS AND METHODS RELATING THERETO | NEUROCRINE BIOSCIENCES INC (US) | 2012-03-07 | — | — | EP | disclosed |