Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.62 |
| ▸ | HSD11B1 | P28845 | 8/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | FFAR2 | O15552 | 2/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL694700 | 0.83 | AKR1C1 (0.66) | HDAC4HSD11B1ALDH1A1HDAC1FFAR2 | |
| SCHEMBL4805246 | 0.83 | HDAC4 (0.64) | HDAC4HSD11B1ALDH1A1HDAC1FFAR2 | |
| SCHEMBL11029291 | 0.81 | HDAC4 (0.62) | HDAC4HSD11B1ALDH1A1HDAC1FFAR2 | |
| SCHEMBL12020281 | 0.81 | HDAC4 (0.62) | HDAC4HSD11B1ALDH1A1HDAC1FFAR2 | |
| SCHEMBL1627734 | 0.81 | HDAC4 (0.66) | HDAC4HSD11B1ALDH1A1HDAC1FFAR2 | |
| SCHEMBL503762 | 0.81 | AKR1C1 (0.68) | HDAC4HSD11B1ALDH1A1HDAC1FFAR2 | |
| Hydrochloric Acid SCHEMBL5741878 | 0.79 | AKR1C1 (0.66) | HDAC4HSD11B1ALDH1A1HDAC1FFAR2 | |
| SCHEMBL5862774 | 0.79 | HDAC4 (0.64) | HDAC4HSD11B1ALDH1A1HDAC1FFAR2 | |
| SCHEMBL5844319 | 0.79 | HDAC4 (0.58) | HDAC4HSD11B1ALDH1A1HDAC1FFAR2 | |
| SCHEMBL18307252 | 0.79 | AKR1C1 (0.70) | HDAC4HSD11B1ALDH1A1HDAC1AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015172047-A1 | CYCLIC PEPTIDE COMPOUNDS AND RELATED METHODS, SALTS AND COMPOSITIONS | MERCK SHARP & DOHME CORP. (US) | 2015-11-12 | — | — | WO | disclosed |