Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1726903 | 0.93 | BTK (0.74) | BTKKCNH2 | |
| SCHEMBL1728753 | 0.91 | BTK (0.78) | BTKKCNH2 | |
| SCHEMBL1728409 | 0.91 | BTK (0.80) | BTKKCNH2 | |
| SCHEMBL1726283 | 0.91 | BTK (0.74) | BTKKCNH2 | |
| SCHEMBL1726635 | 0.90 | BTK (0.74) | BTKKCNH2 | |
| SCHEMBL1726959 | 0.87 | BTK (0.76) | BTKKCNH2 | |
| SCHEMBL1729144 | 0.87 | BTK (0.75) | BTKKCNH2 | |
| SCHEMBL1726568 | 0.87 | BTK (0.79) | BTKKCNH2 | |
| SCHEMBL1724931 | 0.86 | BTK (0.78) | BTKKCNH2 | |
| SCHEMBL1724915 | 0.86 | BTK (0.82) | BTKKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2403846-A1 | INHIBITORS OF BRUTON'S TYROSINE KINASE | F. Hoffmann-La Roche AG (CH) | 2012-01-11 | — | — | EP | disclosed |
| WO-2010100070-A1 | INHIBITORS OF BRUTON'S TYROSINE KINASE | F. HOFFMANN-LA ROCHE AG (CH) | 2010-09-10 | — | — | WO | disclosed |