Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MLYCD | O95822 | 7/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18546129 | 1.00 | HDAC3 (0.38) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL16716801 | 0.87 | HDAC3 (0.36) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL10159204 | 0.87 | HDAC3 (0.36) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL12252983 | 0.87 | HDAC3 (0.36) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL24445633 | 0.81 | HDAC3 (0.41) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL16716800 | 0.78 | HDAC3 (0.39) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL12252985 | 0.78 | HDAC3 (0.39) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL16716804 | 0.78 | HDAC3 (0.39) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL27200152 | 0.77 | SLC6A2 (0.31) | CYP2D6 | |
| SCHEMBL11605695 | 0.73 | MGAM (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4356736-A2 | SYNTHESIS OF BORONATE SALTS | Melinta Therapeutics, Inc. (US) | 2024-04-24 | — | — | EP | disclosed |
| EP-3604316-B1 | SYNTHESIS OF BORONATE SALTS | MELINTA THERAPEUTICS INC (US) | 2023-12-06 | — | — | EP | disclosed |
| US-10669292-B2 | Synthesis of boronate salts and uses thereof | REMPEX PHARMACEUTICALS, INC. (US) | 2020-06-02 | — | — | US | disclosed |
| EP-3604316-A1 | SYNTHESIS OF BORONATE SALTS | Rempex Pharmaceuticals, Inc. (US) | 2020-02-05 | — | — | EP | disclosed |
| US-20200031851-A1 | SYNTHESIS OF BORONATE SALTS AND USES THEREOF | MELINTA SUBSIDIARY CORP. | 2020-01-30 | — | — | US | disclosed |
| US-10385074-B2 | Synthesis of boronate salts and uses thereof | REMPEX PHARMACEUTICALS, INC. (US) | 2019-08-20 | — | — | US | disclosed |
| EP-3140310-B1 | SYNTHESIS OF BORONATE SALTS AND USES THEREOF | REMPEX PHARMACEUTICALS INC (US) | 2019-08-07 | — | — | EP | disclosed |
| US-20170057979-A1 | SYNTHESIS OF BORONATE SALTS AND USES THEREOF | MELINTA SUBSIDIARY CORP. | 2017-03-02 | — | — | US | disclosed |
| US-20170057979-A1 | SYNTHESIS OF BORONATE SALTS AND USES THEREOF | MELINTA SUBSIDIARY CORP. | 2017-03-02 | — | — | US | disclosed |
| WO-2015171430-A1 | SYNTHESIS OF BORONATE SALTS AND USES THEREOF | REMPEX PHARMACEUTICALS, INC. (US) | 2015-11-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200031851-A1 | SYNTHESIS OF BORONATE SALTS AND USES THEREOF | BTD, BCL6B, BRI3BP | HDAC3 2948/4885HDAC1 2341/4885HDAC2 2028/4885 |
| US-20170057979-A1 | SYNTHESIS OF BORONATE SALTS AND USES THEREOF | BTD, BCL6B, BRI3BP | HDAC3 2948/4885HDAC1 2341/4885HDAC2 2028/4885 |
| US-10669292-B2 | Synthesis of boronate salts and uses thereof | BTD, BCL6B, BRI3BP | HDAC3 2948/4885HDAC1 2341/4885HDAC2 2028/4885 |
| US-10385074-B2 | Synthesis of boronate salts and uses thereof | BTD, BCL6B, BRI3BP | HDAC3 2948/4885HDAC1 2341/4885HDAC2 2028/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.