Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.65 |
| ▸ | ERBB2 | P04626 | 6/20 | 0.54 |
| ▸ | GAK | O14976 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17254437 | 1.00 | EGFR (0.65) | EGFRERBB2GAK | |
| SCHEMBL14864925 | 1.00 | EGFR (0.65) | EGFRERBB2GAK | |
| SCHEMBL17254438 | 1.00 | EGFR (0.65) | EGFRERBB2GAK | |
| SCHEMBL14854726 | 0.95 | EGFR (0.63) | EGFRERBB2GAK | |
| SCHEMBL14854723 | 0.95 | EGFR (0.63) | EGFRERBB2GAK | |
| SCHEMBL14854727 | 0.95 | EGFR (0.63) | EGFRERBB2GAK | |
| SCHEMBL21569038 | 0.95 | EGFR (0.63) | EGFRERBB2GAK | |
| SCHEMBL27893977 | 0.92 | EGFR (0.66) | EGFRERBB2GAK | |
| SCHEMBL27911109 | 0.92 | EGFR (0.66) | EGFRERBB2GAK | |
| SCHEMBL14854882 | 0.90 | EGFR (0.77) | EGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3222620-B1 | CYANOQUINOLINE DERIVATIVES | TIANJIN HEMAY ONCOLOGY PHARMACEUTICAL CO LTD (CN) | 2019-11-20 | — | — | EP | claimed |
| US-9187458-B2 | Cyanoquinoline derivatives | TIANJIN HEMAY BIO-TECH CO., LTD. (CN) | 2015-11-17 | — | — | US | claimed |
| CN-102933578-A | Cyanoquinoline derivatives | TIANJIN HEMAY BIO TECH CO LTD | 2013-02-13 | — | — | CN | claimed |
| CN-102933578-A | Cyanoquinoline derivatives | TIANJIN HEMAY BIO TECH CO LTD | 2013-02-13 | — | — | CN | disclosed |