SCHEMBL17255102

SCHEMBL17255102

Cc1cnc(/C=C/c2ccc(-c3ncc(C)o3)cc2)o1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.50
CYP1A2 P05177 3/20 0.50
CYP2C9 P11712 2/20 0.50
MAPT P10636 2/20 0.50
CYP3A4 P08684 1/20 0.50
HPGD P15428 6/20 0.43
SMN1; SMN2 Q16637 6/20 0.43
NPC1 O15118 5/20 0.43
RAB9A P51151 5/20 0.43
ALDH1A1 P00352 3/20 0.36
MEN1 O00255 1/20 0.36
TP53 P04637 1/20 0.36
GAA P10253 1/20 0.36
STAT1 P42224 1/20 0.36
KMT2A Q03164 1/20 0.36
HSD17B10 Q99714 1/20 0.36
ALOX15 P16050 1/20 0.35
TSHR P16473 1/20 0.35
CASP1 P29466 1/20 0.35
CYP2C19 P33261 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17255104 1.00 KDM4E (0.50) KDM4ECYP1A2CYP2C9MAPTCYP3A4
SCHEMBL17255100 0.78 TDP1 (0.30) TDP1
SCHEMBL17255099 0.78 TDP1 (0.30) TDP1
SCHEMBL23291937 0.78 BRD4 (0.44) KDM4ECYP1A2CYP2C9MAPTCYP3A4
SCHEMBL13183698 0.75 NPC1 (0.58) KDM4ECYP1A2CYP2C9MAPTCYP3A4
Ammonia Solution, Strong SCHEMBL28862556 0.73 NPC1 (0.56) KDM4ECYP1A2CYP2C9MAPTCYP3A4
SCHEMBL1435942 0.72 NPC1 (0.52) KDM4ECYP1A2CYP2C9HPGDSMN1; SMN2
SCHEMBL5542665 0.72 KDM4E (0.57) KDM4EHPGDSMN1; SMN2NPC1RAB9A
SCHEMBL13385756 0.72 TSHR (0.60) KDM4ECYP1A2CYP2C9MAPTHPGD
SCHEMBL9863132 0.72 USP7 (0.49) KDM4EMAPTHPGDSMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2944477-B1 MULTICOLOR THERMAL RECORDING MATERIAL, AND METHOD FOR COLOR FORMATION OF SAID MULTICOLOR THERMAL RECORDING MATERIAL OJI HOLDINGS CORP (JP) 2019-04-10 EP disclosed
US-9387714-B2 Multicolor thermal recording material, and method for color formation of said multicolor thermal recording material Oji Holdings Corporation (JP) 2016-07-12 US disclosed
US-20150343825-A1 MULTICOLOR THERMAL RECORDING MATERIAL, AND METHOD FOR COLOR FORMATION OF SAID MULTICOLOR THERMAL RECORDING MATERIAL Oji Holdings Corporation (JP) 2015-12-03 US disclosed
EP-2944477-A1 MULTICOLOR THERMAL RECORDING MATERIAL, AND METHOD FOR COLOR FORMATION OF SAID MULTICOLOR THERMAL RECORDING MATERIAL Oji Holdings Corporation (JP) 2015-11-18 EP disclosed