Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 20/20 | 0.62 |
| ▸ | PRKCD | Q05655 | 14/20 | 0.62 |
| ▸ | PRKCB | P05771 | 1/20 | 0.56 |
| ▸ | LCK | P06239 | 1/20 | 0.56 |
| ▸ | PRKCH | P24723 | 1/20 | 0.56 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17255770 | 0.91 | PRKCQ (0.61) | PRKCQPRKCDPRKCBLCKPRKCH | |
| SCHEMBL2986411 | 0.86 | PRKCQ (0.67) | PRKCQPRKCDPRKCBLCKPRKCH | |
| SCHEMBL2987200 | 0.86 | PRKCQ (0.67) | PRKCQPRKCDPRKCBLCKPRKCH | |
| SCHEMBL2984021 | 0.84 | PRKCQ (0.82) | PRKCQPRKCDPRKCBLCKPRKCH | |
| SCHEMBL2980493 | 0.82 | PRKCQ (0.71) | PRKCQPRKCDPRKCBLCKPRKCH | |
| SCHEMBL2981371 | 0.82 | PRKCQ (0.71) | PRKCQPRKCDPRKCBLCKPRKCH | |
| SCHEMBL2984750 | 0.81 | PRKCQ (0.70) | PRKCQPRKCDPRKCBLCKPRKCH | |
| SCHEMBL2982163 | 0.81 | PRKCQ (0.67) | PRKCQPRKCDPRKCBLCKPRKCH | |
| SCHEMBL2972926 | 0.80 | PRKCQ (0.68) | PRKCQPRKCDPRKCBLCKPRKCH | |
| SCHEMBL2988542 | 0.80 | PRKCQ (0.70) | PRKCQPRKCDPRKCBLCKPRKCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2029543-B1 | SUBSTITUTED 3-CYANOPYRIDINES AS PROTEIN KINASE INHIBITORS | WYETH LLC (US) | 2015-11-18 | — | — | EP | claimed |