Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 7/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | NAMPT | P43490 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19465043 | 0.82 | HPGD (0.58) | HPGDKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL3457192 | 0.81 | NAMPT (0.53) | HPGDKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL7982093 | 0.80 | NAMPT (0.57) | HPGDKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL6112673 | 0.77 | NAMPT (0.54) | HPGDKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL15992236 | 0.76 | PPARG (0.55) | HPGDKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8360112 | 0.76 | NAMPT (0.61) | HPGDKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL10722498 | 0.75 | HDAC6 (0.77) | KMT2AMEN1SMN1; SMN2NAMPT | |
| SCHEMBL4288472 | 0.74 | HPGD (0.55) | HPGDALDH1A1LMNASMN1; SMN2NPC1 | |
| SCHEMBL16318591 | 0.74 | NAMPT (0.60) | HPGDKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL4287093 | 0.74 | HPGD (0.60) | HPGDALDH1A1LMNASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2403852-A1 | 3H-IMIDAZO [4, 5 -C]PYRIDINE- 6 -CARBOXAMIDES AS ANTI- INFLAMMATORY AGENTS | Boehringer Ingelheim International GmbH (DE) | 2012-01-11 | — | — | EP | disclosed |