SCHEMBL17258665

SCHEMBL17258665

Cc1cnc(I)[nH]1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10021906 0.71 SMPD3 (0.48)
SCHEMBL19116700 0.67 BRS3 (0.33)
SCHEMBL12060188 0.67
SCHEMBL12778262 0.67
SCHEMBL726801 0.67
SCHEMBL10719490 0.67
SCHEMBL12778263 0.67
SCHEMBL12068232 0.63
SCHEMBL11855109 0.63
SCHEMBL2282179 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250333405-A1 ANTAGONISTS OF GPR39 PROTEIN VASOCARDEA INC (US) 2025-10-30 US disclosed
EP-4423090-A2 ANTAGONISTS OF GPR39 PROTEIN Vasocardea, Inc. (US) 2024-09-04 EP disclosed
US-20230242548-A1 COMPOSITIONS AND METHODS FOR TREATING CANCER THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2023-08-03 US disclosed
WO-2023076219-A2 ANTAGONISTS OF GPR39 PROTEIN VASOCARDEA, INC. (US) 2023-05-04 WO disclosed
WO-2023076219-A2 ANTAGONISTS OF GPR39 PROTEIN VASOCARDEA, INC. (US) 2023-05-04 WO disclosed
EP-3143021-B1 PYRAZOLOPYRIDINES AND PYRAZOLOPYRIMIDINES PFIZER (US) 2019-06-12 EP disclosed
US-10022376-B2 Pyrazolopyridines and pyrazolopyrimidines PFIZER INC. (US) 2018-07-17 US disclosed
US-10020456-B2 Ether-based polymers as photo-crosslinkable dielectrics BASF SE (DE) 2018-07-10 US disclosed
US-20170250358-A1 ETHER-BASED POLYMERS AS PHOTO-CROSSLINKABLE DIELECTRICS BASF SE (DE) 2017-08-31 US disclosed
CN-107056785-A It is used as the heterocyclic compound of IDO and TDO inhibitor 杭州英创医药科技有限公司 2017-08-18 CN disclosed
EP-2900656-B1 SPIRO RING COMPOUNDS AS HEPATITIS C VIRUS (HCV) INHIBITORS SUNSHINE LAKE PHARMA CO LTD (CN) 2017-05-17 EP disclosed
EP-3143021-A1 PYRAZOLOPYRIDINES AND PYRAZOLOPYRIMIDINES Pfizer Inc (US) 2017-03-22 EP disclosed
US-20170071946-A1 PYRAZOLOPYRIDINES AND PYRAZOLOPYRIMIDINES PFIZER INC. (US) 2017-03-16 US disclosed
US-9518052-B2 Pyrazolopyridines and pyrazolopyrimidines PFIZER INC. (US) 2016-12-13 US disclosed
EP-2410844-B1 INHIBITORS OF HEPATITIS C VIRUS REPLICATION MERCK SHARP & DOHME (US) 2016-03-23 EP disclosed
US-20150329542-A1 PYRAZOLOPYRIDINES AND PYRAZOLOPYRIMIDINES PFIZER INC. 2015-11-19 US disclosed
WO-2015173683-A1 PYRAZOLOPYRIDINES AND PYRAZOLOPYRIMIDINES PFIZER INC. (US) 2015-11-19 WO disclosed
CN-104619707-A Condensed ring heterocyclic compound KYOWA HAKKO KIRIN CO LTD 2015-05-13 CN disclosed
CN-1315955-A Novel carbapenem derivatives MEIJI SEIKA KAISHA (JP) 2001-10-03 CN disclosed