Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 3/20 | 0.32 |
| ▸ | CES1 | P23141 | 3/20 | 0.32 |
| ▸ | LPL | P06858 | 1/20 | 0.31 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5487541 | 0.92 | ANPEP (0.55) | ANPEPTSHRTHRBSMN1; SMN2LMNA | |
| SCHEMBL17287861 | 0.81 | — | — | |
| SCHEMBL16521392 | 0.79 | ANPEP (0.42) | ANPEPTSHRTHRBSMN1; SMN2LMNA | |
| SCHEMBL9561943 | 0.79 | — | — | |
| SCHEMBL10584179 | 0.79 | — | — | |
| SCHEMBL21154909 | 0.77 | ANPEP (0.40) | ANPEPTSHRTHRBLMNAALDH1A1 | |
| SCHEMBL254277 | 0.75 | ANPEP (0.39) | ANPEPTSHRTHRBSMN1; SMN2ALDH1A1 | |
| SCHEMBL8522636 | 0.75 | ANPEP (0.39) | ANPEPTSHRSMN1; SMN2CES2CES1 | |
| SCHEMBL2053711 | 0.75 | ANPEP (0.39) | ANPEPTSHRTHRBSMN1; SMN2 | |
| SCHEMBL14354252 | 0.75 | ANPEP (0.39) | ANPEPTSHRTHRBSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10293048-B2 | Pharmaceutical compositions comprising boronic acid compounds | DR. REDDY'S LABORATORIES LIMITED (IN) | 2019-05-21 | — | — | US | disclosed |
| EP-2819673-B1 | PHARMACEUTICAL COMPOSITIONS COMPRISING BORONIC ACID COMPOUNDS | REDDYS LAB LTD DR (IN) | 2016-09-07 | — | — | EP | disclosed |
| US-20150051172-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING BORONIC ACID COMPOUNDS | DR. REDDY'S LABORATORIES LIMITED (IN) | 2015-02-19 | — | — | US | disclosed |
| EP-2819673-A2 | PHARMACEUTICAL COMPOSITIONS COMPRISING BORONIC ACID COMPOUNDS | Dr. Reddy's Laboratories Ltd. (IN) | 2015-01-07 | — | — | EP | disclosed |
| WO-2013128419-A2 | PHARMACEUTICAL COMPOSITIONS COMPRISING BORONIC ACID COMPOUNDS | DR. REDDY'S LABORATORIES LIMITED (IN) | 2013-09-06 | — | — | WO | disclosed |
| US-20110178470-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING BORONIC ACID COMPOUNDS | DR. REDDY'S LABORATORIES LTD. (IN) | 2011-07-21 | — | — | US | disclosed |
| EP-2344165-A2 | PHARMACEUTICAL COMPOSITIONS COMPRISING BORONIC ACID COMPOUNDS | Dr. Reddy's Laboratories, Ltd. (IN) | 2011-07-20 | — | — | EP | disclosed |
| WO-2010039762-A2 | PHARMACEUTICAL COMPOSITIONS COMPRISING BORONIC ACID COMPOUNDS | DR. REDDY'S LABORATORIES LTD. (IN) | 2010-04-08 | — | — | WO | disclosed |
| US-6693210-B2 | USING PALLADIUM, NICKEL PHOSPHINE COMPLEX AS CATALYSTS | MITSUBISHI RAYON CO., LTD. (JP) | 2004-02-17 | — | — | US | disclosed |
| US-20030065208-A1 | Using palladium, nickel phosphine complex as catalysts | MITSUBISHI RAYON CO., LTD. (JP) | 2003-04-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10293048-B2 | Pharmaceutical compositions comprising boronic acid compounds | MALT1, BCL6, BCL6B | ANPEP 4054/4885TSHR 3420/4885THRB 635/4885 |
| US-20030065208-A1 | Using palladium, nickel phosphine complex as catalysts | PDCD1LG2, PIK3CA, PDCD1 | ANPEP 2357/4885TSHR 2980/4885THRB 4059/4885 |
| US-20150051172-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING BORONIC ACID COMPOUNDS | MALT1, BCL6, BCL6B | ANPEP 4054/4885TSHR 3420/4885THRB 635/4885 |
| US-20110178470-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING BORONIC ACID COMPOUNDS | BCL6, BBC3, RB1 | ANPEP 3875/4885TSHR 4238/4885THRB 3304/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.