Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASIC3 | Q9UHC3 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.34 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | NQO1 | P15559 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 4/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5683034 | 0.79 | APP (0.55) | ASIC3CYP1A2ATMTDP1L3MBTL1 | |
| SCHEMBL17263313 | 0.79 | CYP2A6 (0.31) | — | |
| SCHEMBL456129 | 0.77 | APP (0.57) | CYP1A2CYP1A1CYP1B1APPGRM5 | |
| SCHEMBL442909 | 0.76 | APP (0.50) | ASIC3CYP1A2CYP1B1ATMTDP1 | |
| SCHEMBL652147 | 0.72 | ELANE (0.41) | CYP1A2CYP1A1CYP1B1TDP1ELANE | |
| SCHEMBL18091340 | 0.72 | APP (0.50) | ASIC3CYP1A2CYP1A1CYP1B1ATM | |
| SCHEMBL14380097 | 0.71 | GRM5 (0.51) | APPGRM5 | |
| SCHEMBL652959 | 0.70 | ELANE (0.37) | CYP1A2TDP1ELANENQO1GRM5 | |
| SCHEMBL19941921 | 0.70 | CHAT (0.39) | CYP1A2CYP1A1CYP1B1TDP1L3MBTL1 | |
| SCHEMBL4585249 | 0.70 | HSD17B10 (0.44) | KDM4EALDH1A1TP53CYP3A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9190622-B2 | Hybrid ambipolar TFTs | MERCK PATENT GMBH (DE) | 2015-11-17 | — | — | US | disclosed |