Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
| ▸ | MPO | P05164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1721867 | 0.88 | MCHR1 (0.43) | MCHR1LMNASCN9ANPSR1AMY1A | |
| SCHEMBL9989229 | 0.80 | MCHR1 (0.54) | MCHR1LMNASMN1; SMN2MAPT | |
| SCHEMBL2387820 | 0.71 | MCHR1 (0.47) | MCHR1 | |
| SCHEMBL1727614 | 0.71 | JAK1 (0.34) | MCHR1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL12257858 | 0.70 | MCHR1 (0.72) | MCHR1 | |
| SCHEMBL9995127 | 0.69 | MCHR1 (0.54) | MCHR1LMNASMN1; SMN2MAPTPOLB | |
| SCHEMBL2171507 | 0.69 | KDM4E (0.43) | MEN1KMT2AMAPT | |
| SCHEMBL1144636 | 0.69 | MCHR1 (0.49) | MCHR1 | |
| SCHEMBL12043438 | 0.68 | MCHR1 (0.57) | MCHR1 | |
| Hydrochloric Acid SCHEMBL9988998 | 0.68 | MCHR1 (0.57) | MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2406233-A1 | AZA PYRIDONE ANALOGS USEFUL AS MELANIN CONCENTRATING HORMONE RECEPTOR-1 ANTAGONISTS | Bristol-Myers Squibb Company (US) | 2012-01-18 | — | — | EP | disclosed |
| WO-2010104818-A1 | AZA PYRIDONE ANALOGS USEFUL AS MELANIN CONCENTRATING HORMONE RECEPTOR-1 ANTAGONISTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2010-09-16 | — | — | WO | disclosed |