Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.47 |
| ▸ | MIF | P14174 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.35 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 1,5-Pentanediol SCHEMBL28135610 | 1.00 | — | — | |
| 1,6-Hexanediol SCHEMBL28160475 | 1.00 | — | — | |
| 1,4-Butanediol SCHEMBL9863115 | 0.94 | SMN1; SMN2 (0.54) | TSHRALDH1A1LMNAHSD17B10MEN1 | |
| SCHEMBL5078041 | 0.94 | TSHR (0.61) | TSHRALDH1A1LMNAHSD17B10MEN1 | |
| SCHEMBL658537 | 0.94 | TSHR (0.61) | TSHRALDH1A1LMNAHSD17B10MEN1 | |
| SCHEMBL25302278 | 0.94 | TSHR (0.61) | TSHRALDH1A1LMNAHSD17B10MEN1 | |
| SCHEMBL21879690 | 0.94 | TSHR (0.61) | TSHRALDH1A1LMNAHSD17B10MEN1 | |
| 1,4-Butanediol SCHEMBL21630075 | 0.94 | TSHR (0.61) | TSHRALDH1A1LMNAHSD17B10MEN1 | |
| SCHEMBL21462773 | 0.94 | TSHR (0.61) | TSHRALDH1A1LMNAHSD17B10MEN1 | |
| 1,5-Pentanediol SCHEMBL15847271 | 0.94 | TSHR (0.61) | TSHRALDH1A1LMNAHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119750607-A | Nano rod-shaped ZSM-48 molecular sieve, preparation method thereof, hydroisomerization catalyst and application thereof | 国家能源集团宁夏煤业有限责任公司 | 2025-04-04 | — | — | CN | claimed |
| CN-119750607-A | Nano rod-shaped ZSM-48 molecular sieve, preparation method thereof, hydroisomerization catalyst and application thereof | 国家能源集团宁夏煤业有限责任公司 | 2025-04-04 | — | — | CN | disclosed |
| EP-3545958-B1 | SALTS OF POTASSIUM ATP CHANNEL OPENERS AND USES THEREOF | ESSENTIALIS INC (US) | 2024-07-10 | — | — | EP | disclosed |
| US-11786536-B2 | Salts of potassium ATP channel openers and uses thereof | ESSENTIALIS, INC. (US) | 2023-10-17 | — | — | US | disclosed |
| US-20220047605-A1 | SALTS OF POTASSIUM ATP CHANNEL OPENERS AND USES THEREOF | SOLENO THERAPEUTICS, INC. | 2022-02-17 | — | — | US | disclosed |
| US-11045478-B2 | Salts of potassium ATP channel openers and uses thereof | ESSENTIALIS, INC. (US) | 2021-06-29 | — | — | US | disclosed |
| US-20200222417-A1 | SALTS OF POTASSIUM ATP CHANNEL OPENERS AND USES THEREOF | SOLENO THERAPEUTICS, INC. | 2020-07-16 | — | — | US | disclosed |
| EP-3545958-A1 | SALTS OF POTASSIUM ATP CHANNEL OPENERS AND USES THEREOF | Essentialis, Inc. (US) | 2019-10-02 | — | — | EP | disclosed |
| US-20190117665-A1 | SALTS OF POTASSIUM ATP CHANNEL OPENERS AND USES THEREOF | SOLENO THERAPEUTICS, INC. | 2019-04-25 | — | — | US | disclosed |
| EP-2404604-B1 | Salts of potassium ATP channel openers and uses thereof | ESSENTIALIS INC (US) | 2019-02-06 | — | — | EP | disclosed |
| EP-2170341-A1 | SALTS OF POTASSIUM ATP CHANNEL OPENERS AND USES THEREOF | Essentialis, Inc. (US) | 2010-04-07 | — | — | EP | disclosed |
| US-20100028429-A1 | SALTS OF POTASSIUM ATP CHANNEL OPENERS AND USES THEREOF | ESSENTIALIS, INC. | 2010-02-04 | — | — | US | disclosed |
| US-7572789-B2 | Salts of potassium ATP channel openers and uses thereof | ESSENTIALIS, INC. (US) | 2009-08-11 | — | — | US | disclosed |
| US-20090148526-A1 | SALTS OF POTASSIUM ATP CHANNEL OPENERS AND USES THEREOF | ESSENTIALIS, INC. | 2009-06-11 | — | — | US | disclosed |
| US-20090062264-A1 | SALTS OF POTASSIUM ATP CHANNEL OPENERS AND USES THEREOF | SOLENO THERAPEUTICS, INC. | 2009-03-05 | — | — | US | disclosed |
| EP-1968601-A4 | SALTS OF POTASSIUM ATP CHANNEL OPENERS AND USES THEREOF | ESSENTIALIS INC (US) | 2009-02-25 | — | — | EP | disclosed |
| WO-2009006483-A1 | SALTS OF POTASSIUM ATP CHANNEL OPENERS AND USES THEREOF | ESSENTIALIS, INC. (US) | 2009-01-08 | — | — | WO | disclosed |
| EP-1968601-A2 | SALTS OF POTASSIUM ATP CHANNEL OPENERS AND USES THEREOF | Essentialis, Inc. (US) | 2008-09-17 | — | — | EP | disclosed |
| US-20070191351-A1 | SALTS OF POTASSIUM ATP CHANNEL OPENERS AND USES THEREOF | SOLENO THERAPEUTICS, INC. | 2007-08-16 | — | — | US | disclosed |
| WO-2007081521-A2 | SALTS OF POTASSIUM ATP CHANNEL OPENERS AND USES THEREOF | ESSENTIALIS, INC. (US) | 2007-07-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100028429-A1 | SALTS OF POTASSIUM ATP CHANNEL OPENERS AND USES THEREOF | KCNJ1, KCNJ11, KCNJ2 | TSHR 2951/4885ALDH1A1 889/4885LMNA 3006/4885 |
| US-20220047605-A1 | SALTS OF POTASSIUM ATP CHANNEL OPENERS AND USES THEREOF | KCNJ1, KCNJ11, KCNJ2 | TSHR 2951/4885ALDH1A1 889/4885LMNA 3006/4885 |
| US-20200222417-A1 | SALTS OF POTASSIUM ATP CHANNEL OPENERS AND USES THEREOF | KCNJ1, KCNJ11, KCNJ2 | TSHR 2951/4885ALDH1A1 889/4885LMNA 3006/4885 |
| US-20070191351-A1 | SALTS OF POTASSIUM ATP CHANNEL OPENERS AND USES THEREOF | KCNJ1, KCNJ11, KCNJ2 | TSHR 2951/4885ALDH1A1 889/4885LMNA 3006/4885 |
| US-20090062264-A1 | SALTS OF POTASSIUM ATP CHANNEL OPENERS AND USES THEREOF | KCNJ1, KCNJ11, KCNJ2 | TSHR 2951/4885ALDH1A1 889/4885LMNA 3006/4885 |
| US-20190117665-A1 | SALTS OF POTASSIUM ATP CHANNEL OPENERS AND USES THEREOF | KCNJ1, KCNJ11, KCNJ2 | TSHR 2951/4885ALDH1A1 889/4885LMNA 3006/4885 |
| US-11786536-B2 | Salts of potassium ATP channel openers and uses thereof | KCNJ1, KCNJ11, KCNJ2 | TSHR 2951/4885ALDH1A1 889/4885LMNA 3006/4885 |
| US-20090148526-A1 | SALTS OF POTASSIUM ATP CHANNEL OPENERS AND USES THEREOF | KCNJ1, KCNJ11, KCNJ2 | TSHR 2951/4885ALDH1A1 889/4885LMNA 3006/4885 |
| US-11045478-B2 | Salts of potassium ATP channel openers and uses thereof | KCNJ1, KCNJ11, KCNJ2 | TSHR 2951/4885ALDH1A1 889/4885LMNA 3006/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.