SCHEMBL17265649

SCHEMBL17265649

CC1CN(c2ccc(N)cc2)C(C)CN1c1ccc(N)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.42
ALDH1A1 P00352 6/20 0.42
GFER P55789 4/20 0.42
KDM4E B2RXH2 4/20 0.42
KMT2A Q03164 4/20 0.42
GAA P10253 3/20 0.42
ADRA2C P18825 1/20 0.42
PTK2B Q14289 1/20 0.42
ESR2 Q92731 1/20 0.42
MEN1 O00255 3/20 0.39
HTT P42858 2/20 0.39
RECQL P46063 2/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
TP53 P04637 2/20 0.39
NPC1 O15118 1/20 0.39
USP2 O75604 1/20 0.39
POLB P06746 1/20 0.39
THRB P10828 1/20 0.39
ALOX15 P16050 1/20 0.39
RAB9A P51151 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1048008 0.90 MAPT (0.40) MAPTALDH1A1GFERKDM4EKMT2A
SCHEMBL12424155 0.90 MAPT (0.40) MAPTALDH1A1GFERKDM4EKMT2A
SCHEMBL1048007 0.90 MAPT (0.40) MAPTALDH1A1GFERKDM4EKMT2A
SCHEMBL20873919 0.83 GFER (0.37) MAPTGFERMAPK1CASP6
SCHEMBL6385406 0.81 GFER (0.35) MAPTALDH1A1GFERKDM4EKMT2A
SCHEMBL20884848 0.81 KDM4E (0.52) MAPTALDH1A1GFERKDM4EKMT2A
SCHEMBL188063 0.81 KDM4E (0.52) MAPTALDH1A1GFERKDM4EKMT2A
SCHEMBL189064 0.81 KDM4E (0.52) MAPTALDH1A1GFERKDM4EKMT2A
SCHEMBL16853407 0.79 HDAC1 (0.39) MAPTALDH1A1GFERKDM4EKMT2A
SCHEMBL6606179 0.77 GFER (0.37) MAPTALDH1A1GFERKDM4EKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150329781-A1 LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT CHI MEI CORPORATION (TW) 2015-11-19 US disclosed
US-20150329781-A1 LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT CHI MEI CORPORATION (TW) 2015-11-19 US disclosed