⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7875855 | 0.73 | — | — | |
| SCHEMBL65799 | 0.73 | — | — | |
| SCHEMBL2343330 | 0.73 | PIK3CD (0.31) | — | |
| SCHEMBL5146958 | 0.73 | TDP1 (0.32) | — | |
| SCHEMBL2666906 | 0.73 | — | — | |
| SCHEMBL30233192 | 0.71 | — | — | |
| SCHEMBL30233781 | 0.71 | — | — | |
| SCHEMBL1511742 | 0.71 | — | — | |
| SCHEMBL30233194 | 0.71 | — | — | |
| Water SCHEMBL6480646 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2678329-B1 | TRIAZOLOPYRIDINE COMPOUNDS AS PIM KINASE INHIBITORS | ARRAY BIOPHARMA INC (US) | 2015-11-18 | — | — | EP | disclosed |