Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7150846 | 0.80 | OGA (0.45) | OGACA9CA12CA1CA2 | |
| SCHEMBL7147478 | 0.80 | OGA (0.45) | OGACA9CA12CA1CA2 | |
| SCHEMBL7150561 | 0.80 | OGA (0.45) | OGACA9CA12CA1CA2 | |
| SCHEMBL7147483 | 0.80 | OGA (0.45) | OGACA9CA12CA1CA2 | |
| SCHEMBL14049363 | 0.80 | OGA (0.40) | OGACA9CA12CA1CA2 | |
| SCHEMBL12151508 | 0.77 | OGA (0.40) | OGA | |
| SCHEMBL7739256 | 0.77 | OGA (0.50) | OGACA9CA12CA1CA2 | |
| SCHEMBL7739748 | 0.77 | OGA (0.50) | OGACA9CA12CA1CA2 | |
| SCHEMBL12302011 | 0.77 | OGA (0.50) | OGACA9CA12CA1CA2 | |
| SCHEMBL332549 | 0.77 | OGA (0.50) | OGACA9CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015175695-A1 | SMALL MOLECULE COMPOUNDS SELECTIVE AGAINST GRAM-NEGATIVE BACTERIAL INFECTIONS | DEBRABANDER JEF (US) | 2015-11-19 | — | — | WO | disclosed |