SCHEMBL1727150

SCHEMBL1727150

CSCCC(N)C(=O)NC(CCCNC(=N)N)C(=O)NC(Cc1ccccc1)C(=O)N[C@@H](C)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ NPY4R P50391 14/20 0.56
▸ NPY1R P25929 9/20 0.56
▸ NPY5R Q15761 8/20 0.56
▸ NPY2R P49146 5/20 0.56
▸ FNTA P49354 3/20 0.52
▸ FNTB P49356 3/20 0.52
▸ PGGT1B P53609 3/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1940080 1.00 NPY4R (0.56) NPY4RNPY1RNPY5RNPY2RFNTA
SCHEMBL1727152 1.00 NPY4R (0.56) NPY4RNPY1RNPY5RNPY2RFNTA
Acetic Acid SCHEMBL230815 0.98 NPY4R (0.55) NPY4RNPY1RNPY5RNPY2RFNTA
Acetic Acid SCHEMBL8587360 0.98 NPY4R (0.55) NPY4RNPY1RNPY5RNPY2RFNTA
Acetic Acid SCHEMBL230814 0.98 NPY4R (0.55) NPY4RNPY1RNPY5RNPY2RFNTA
Acetic Acid SCHEMBL2341079 0.97 NPY4R (0.54) NPY4RNPY1RNPY5RNPY2RFNTA
Acetic Acid SCHEMBL2341088 0.97 NPY4R (0.54) NPY4RNPY1RNPY5RNPY2RFNTA
SCHEMBL30866932 0.95 NPY4R (0.55) NPY4RNPY1RNPY5RNPY2RFNTA
SCHEMBL29619346 0.93 FNTA (0.60) NPY4RNPY1RNPY5RNPY2RFNTA
SCHEMBL29352845 0.93 FNTA (0.58) NPY4RNPY1RNPY5RNPY2RFNTA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120148576-A1 HUMANIZED ANTI-CD 19 ANTIBODY FORMULATIONS MEDLMMUNE, LLC (US) 2012-06-14 — — US disclosed
EP-2403532-A2 HUMANIZED ANTI-CD19 ANTIBODY FORMULATIONS MedImmune, LLC (US) 2012-01-11 — — EP disclosed
WO-2010102276-A2 HUMANIZED ANTI-CD19 ANTIBODY FORMULATIONS MEDIMMUNE, LLC (US) 2010-09-10 — — WO disclosed
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